Nat Commun: What is the acceptance and effectiveness of the BNT162b2 vaccine by British medical staff?

The COVID-19 pandemic has already had a major impact on the population of the world
.

Among them, health care workers (HCWs) have been particularly affected, so they have been designated as a high priority group by the British Joint Committee on Vaccination and Immunization

immunity

The administration plan of the BNT162B2 vaccine is to inject a dose of 30 micrograms on day 0 and repeat the injection at least 21 days later.
However, due to limited supply, the British government’s strategy is to postpone the second injection until 3 months later
.

Recently, in a single-center cohort study in London, researchers evaluated the absorption and effectiveness of a single-dose BNT162b2 vaccine by British healthcare workers (HCWs) during the high incidence of COVID-19 in the community
.

COVID-19

The results showed that the early absorption rate of medical staff was 62.
3% (1409/2260) , but the absorption rate of different age groups, races and different job roles was significantly different
.

After a vaccine working group implemented specific measures, the absorption rate rose to 72.

The early absorption rate of medical staff was 62.

The Kaplan-Meier curves of the partially vaccinated group and the unvaccinated group were consistent before the 14th day, and continued to diverge before the 42th day

Kaplan-Meier estimates the time when vaccinated and unvaccinated health workers are first infected with COVID-19

Kaplan-Meier estimates vaccinated and unvaccinated health workers first infected time COVID-19 of the Kaplan-Meier estimates of health workers vaccinated and unvaccinated first infection time of COVID-19 infection

Cox regression analysis showed that the risk of contracting COVID-19 among some vaccinated high-risk groups was reduced by 70.

Part of the vaccinated high-risk population has a 70.

In the first-line clinical setting, the BNT162B2 vaccine is effective from 14 days after vaccination, and still has a protective effect within 21 days after the first injection, without the need for a second injection

BNT162B2 vaccine is effective from 14 days after vaccination, and still has a protective effect within 21 days after the first shot.

Original source:

Original source:

Tariq Azamgarhiet al.

Tariq Azamgarhi et al.

 

 

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