NAT MED: Largest Alzheimer's-Related Protein Study Published To Date

To date, our understanding of the pathophysiology of Alzheimer's disease (AD) has not been completerecently, researchers conducted the largest proteomics study of AD to date using quantitative mass spectrometry and co-expression network analysisresearchers have discovered a network of protein slots associated with sugar metabolism, one of the most significant lyses to AD pathology and cognitive impairmentThe module enriches aD genetic risk factors and small glial cells and star-shaped glial cell protein markers associated with anti-inflammatory states, indicating that the biological function sits on behalf of ADin the early stages of the disease, the protein in the module rises in cerebrospinal fluidin the study, which used quantitative proteomics to 2,000 brain and nearly 400 cerebrospinal fluid samples, researchers identified proteins and biological processes in the AD brain that could serve as therapeutic targets for the disease and as biomarkers of cerebrospinal fluid