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Nature Sub-Journal: Functional Motif of Long Non-coding RNA Nron Anti-osteoporosis

 Last Update: 2021-08-10
 Source: Internet
 Author: User

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Long non-coding RNAs are widely involved in a variety of disease processes

Osteoporotic fractures have a catastrophic impact on the health of the elderly

Recently, the regulatory role of lncRNAs in bone homeostasis has been recognized

Here, the author believes that lncRNA Nron is a negative regulator of bone resorption

This study mainly focused on the anti-bone resorption effect and therapeutic potential of Nron and its functional phantom

In summary, the author screened a nncRNA Nron that can inhibit bone resorption in vivo, and evaluated the role of Nron and its functional motifs in the treatment of osteoporosis

references

Fujun Jin et al.

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