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This article is original by Translational Medicine Network.
Please indicate the source for reprinting.
Author: Ashley Introduction: Colorectal cancer is one of the main causes of cancer death.
Successful treatment depends on the stage of diagnosis
.
The incidence of colorectal cancer is increasing, and it has become an important and challenging global public health problem, among which early detection of cancer is of great significance
.
Recent studies have found that colorectal cancer can be more accurately identified through the composition of the microbiome
.
In order to study colorectal cancer more efficiently, microbiome scientists from the University of Tartu have been able to characterize the composition of the microbiome in sample tubes used for colorectal cancer screening to detect fecal occult blood
.
This article was recently published in the journal "Scientific Reports", entitled "Using fecal immunochemical tubes for the analysis of the gut microbiome has the potential to improve colorectal cancer screening"
.
Epidemiological data show that due to the aging of the population and the increasing popularity of Western diets and life>
.
Many countries have begun to invite individuals to participate in population-based screening programs, by analyzing fecal blood through a stool immunochemical test (FIT), and then undergoing colonoscopy to increase early cancer detection
.
The first author of the paper, Kertu Liis Krigul, said: “However, the current screening program faces multiple challenges, including low participation rates, low sensitivity to precancerous or early cancers, and false positive and false negative results
.
Therefore, there is an urgent need for new Highly specific, inexpensive and sensitive non-invasive screening and testing methods to improve the detection of colorectal precancerous lesions and cancers to reduce disease morbidity and mortality
.
"More and more evidence indicates the essence of the microbiome It contributes to the development of colorectal cancer
.
Therefore, the fecal occult blood test with intestinal flora analysis can improve the detection of colorectal cancer
.
In this study, researchers tested FIT tubes used in the National Colorectal Cancer Screening Program on volunteers and found that these are also applicable to microbiome analysis
.
However, the actual ability to use this collection method to detect cancer-specific bacterial signatures will now be studied in patients with or without CRC
.
Krigul said: "The use of additional microbial-based biomarkers to detect colorectal cancer may make the diagnosis of colorectal cancer more sensitive and affordable
.
" Stool samples from the colorectal cancer screening program are an excellent resource for discovering biomarkers.
It may be helpful for early detection of cancer or detection before it occurs (precancerous state)
.
The author hypothesizes that stool samples from FIT test tubes can also be used to discover biomarkers and study the gut microbiome in other digestive diseases (such as pancreatic cancer, inflammatory bowel disease, and cholangitis) that have previously been associated with the gut microbiome In this case, it is usually impossible to send samples by mail and use fresh frozen samples
.
Krigul said: "Obtaining an accurate microbiome map from the FIT tubes used in several European screening projects is a crucial step for new research possibilities and future biomarker discovery in order to collect the microbiome.
.
"Reference material: https://medicalxpress.
com/news/2021-10-accurately-colorectal-cancer-microbiome-composition.
html Note: This article aims to introduce medical research progress and cannot be used as a reference for treatment plans
.
If you need health guidance , Please go to a regular hospital for treatment
.
The
popular article Diagnostic Test [The Lancet] calls for action! Nearly half of the world’s people cannot get basic diagnosis of many common diseases.
Can the COVID-19 pandemic help change the diagnosis? Immunotherapy [ Nature Sub-Journal] Lung epithelial cells control lung immunity? This will lay the foundation for the treatment of a variety of lung diseases! Tumor research [Research] Be vigilant! Summarizing 30 years of big data: Esophageal adenocarcinoma is showing a younger trend Medical trends [News] In 2021, the Nobel Prize in Physiology or Medicine will be announced, and pain receptors won! Intestinal health [PNAS] research has discovered the "second brain" that exists in the intestine, and its glial will open up new ways to treat intestinal diseases! Tumor research [Nature Sub-Journal] Using single-cell multi-omics to study tumor cells new ideas, top-level teams such as Harvard Medical School create a precedent! Cancer research [Science] protein may become a new breakthrough in cancer treatment! New coronavirus [Science] SARS- The truth about the source of CoV-2 is revealed? The coronavirus that is the closest to the new coronavirus has been found in Laos bats so far, with a matching rate of 96.
8%! The new crown virus [The BMJ] has an inoculation rate of 78% in Israel, why the epidemic is still out of control? New crown vaccine Is there a need to worry about the efficacy? Is it necessary to strengthen the needle? Organoid Research [Nature Sub-Journal] The 3D pancreatic cancer tumor model cultivated by an international team of scientists including Shanghai Jiaotong University can effectively improve the treatment of pancreatic cancer.
Tumor research [ Science Journal】Salt has the effect of inhibiting tumors? Scientists will explain unexpected discoveries through mouse experiments! Recommendation·Activity The 3rd Shanghai International Cancer Conference The 5th Modern Clinical Molecular Diagnosis Symposium
Please indicate the source for reprinting.
Author: Ashley Introduction: Colorectal cancer is one of the main causes of cancer death.
Successful treatment depends on the stage of diagnosis
.
The incidence of colorectal cancer is increasing, and it has become an important and challenging global public health problem, among which early detection of cancer is of great significance
.
Recent studies have found that colorectal cancer can be more accurately identified through the composition of the microbiome
.
In order to study colorectal cancer more efficiently, microbiome scientists from the University of Tartu have been able to characterize the composition of the microbiome in sample tubes used for colorectal cancer screening to detect fecal occult blood
.
This article was recently published in the journal "Scientific Reports", entitled "Using fecal immunochemical tubes for the analysis of the gut microbiome has the potential to improve colorectal cancer screening"
.
Epidemiological data show that due to the aging of the population and the increasing popularity of Western diets and life>
.
Many countries have begun to invite individuals to participate in population-based screening programs, by analyzing fecal blood through a stool immunochemical test (FIT), and then undergoing colonoscopy to increase early cancer detection
.
The first author of the paper, Kertu Liis Krigul, said: “However, the current screening program faces multiple challenges, including low participation rates, low sensitivity to precancerous or early cancers, and false positive and false negative results
.
Therefore, there is an urgent need for new Highly specific, inexpensive and sensitive non-invasive screening and testing methods to improve the detection of colorectal precancerous lesions and cancers to reduce disease morbidity and mortality
.
"More and more evidence indicates the essence of the microbiome It contributes to the development of colorectal cancer
.
Therefore, the fecal occult blood test with intestinal flora analysis can improve the detection of colorectal cancer
.
In this study, researchers tested FIT tubes used in the National Colorectal Cancer Screening Program on volunteers and found that these are also applicable to microbiome analysis
.
However, the actual ability to use this collection method to detect cancer-specific bacterial signatures will now be studied in patients with or without CRC
.
Krigul said: "The use of additional microbial-based biomarkers to detect colorectal cancer may make the diagnosis of colorectal cancer more sensitive and affordable
.
" Stool samples from the colorectal cancer screening program are an excellent resource for discovering biomarkers.
It may be helpful for early detection of cancer or detection before it occurs (precancerous state)
.
The author hypothesizes that stool samples from FIT test tubes can also be used to discover biomarkers and study the gut microbiome in other digestive diseases (such as pancreatic cancer, inflammatory bowel disease, and cholangitis) that have previously been associated with the gut microbiome In this case, it is usually impossible to send samples by mail and use fresh frozen samples
.
Krigul said: "Obtaining an accurate microbiome map from the FIT tubes used in several European screening projects is a crucial step for new research possibilities and future biomarker discovery in order to collect the microbiome.
.
"Reference material: https://medicalxpress.
com/news/2021-10-accurately-colorectal-cancer-microbiome-composition.
html Note: This article aims to introduce medical research progress and cannot be used as a reference for treatment plans
.
If you need health guidance , Please go to a regular hospital for treatment
.
The
popular article Diagnostic Test [The Lancet] calls for action! Nearly half of the world’s people cannot get basic diagnosis of many common diseases.
Can the COVID-19 pandemic help change the diagnosis? Immunotherapy [ Nature Sub-Journal] Lung epithelial cells control lung immunity? This will lay the foundation for the treatment of a variety of lung diseases! Tumor research [Research] Be vigilant! Summarizing 30 years of big data: Esophageal adenocarcinoma is showing a younger trend Medical trends [News] In 2021, the Nobel Prize in Physiology or Medicine will be announced, and pain receptors won! Intestinal health [PNAS] research has discovered the "second brain" that exists in the intestine, and its glial will open up new ways to treat intestinal diseases! Tumor research [Nature Sub-Journal] Using single-cell multi-omics to study tumor cells new ideas, top-level teams such as Harvard Medical School create a precedent! Cancer research [Science] protein may become a new breakthrough in cancer treatment! New coronavirus [Science] SARS- The truth about the source of CoV-2 is revealed? The coronavirus that is the closest to the new coronavirus has been found in Laos bats so far, with a matching rate of 96.
8%! The new crown virus [The BMJ] has an inoculation rate of 78% in Israel, why the epidemic is still out of control? New crown vaccine Is there a need to worry about the efficacy? Is it necessary to strengthen the needle? Organoid Research [Nature Sub-Journal] The 3D pancreatic cancer tumor model cultivated by an international team of scientists including Shanghai Jiaotong University can effectively improve the treatment of pancreatic cancer.
Tumor research [ Science Journal】Salt has the effect of inhibiting tumors? Scientists will explain unexpected discoveries through mouse experiments! Recommendation·Activity The 3rd Shanghai International Cancer Conference The 5th Modern Clinical Molecular Diagnosis Symposium
