Nature Sub-Journal: The World's Largest Collection of Live Tumors for Patients with Prostate Cancer

Researchers at Monash University have established one of the world's largest collections of live tumors for prostate cancer patients, which speeds up the testing of new prostate cancer treatments and allows patients to benefit more quickly

Prostate cancer is one of the most common cancers and one of the most difficult to study in the laboratory.

The PDX collection (patient-derived xenograft) developed by the multidisciplinary consortium led by Professor Gail Risbridger and Associate Professor Renea Taylor of the Monash Biomedical Discovery Institute (BDI) now includes 59 tumors and 30 were collected between 2012 and 2020 It is currently one of the countries with the largest collection of prostate cancer models in the world

The complete features of the PDX collection are published in Nature Communications

PDXs are a lasting resource for new cancer models and can be shared with other academic researchers or pharmaceutical companies

The project started and ended with patients like EJ Whitten

Ted Whitten, executive director and founder of the White Foundation, congratulated Monash University's Institute of Biomedical Discovery on the latest findings in prostate cancer research

Senior author Dr.

The success of the project is based on the collaboration between scientists and clinicians, such as surgeons and oncologists from Monash, the Cabrini Institute and Peter McCallum Cancer Center, as well as patients and oncologists who have generously donated cancer tissues.

Original search:

The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology.