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More than a year has passed since the COVID-19 pandemic caused by the new coronavirus (SARS-CoV-2), and an unprecedented number of large-scale vaccination efforts are being carried out globally
In the past, people used passive monitoring systems to collect information on vaccine safety, which relied on voluntary reports by individuals vaccinated, which would result in incomplete records
On August 25, 2021, the Israeli Clalit Institute and the research team of Harvard University published a research paper titled: Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting in the New England Journal of Medicine (NEJM)
The study used the comprehensive database of Israel's largest healthcare organization to evaluate the safety of the BNT162b2 mRNA vaccine and found that the vaccine was not associated with the increased risk of most adverse events
After the new coronavirus infection, the risk of potentially serious adverse events such as myocarditis and many other serious adverse events is greatly increased, and the vaccine actually reduces these risks
In order to provide the necessary background to explain the vaccine safety results, this study examined for the first time various adverse events between vaccinated individuals and unvaccinated individuals infected with the coronavirus
The vaccination cohort included 1,736,832 people, with a median age of 43 years
Compared with the unvaccinated group, the risk of adverse events in the vaccinated group was significantly higher than that in the unvaccinated group: myocarditis occurred 2.
In order to provide the background of the above vaccine safety results, the research team conducted a separate analysis-the new crown infection cohort analysis
The research team found that myocarditis is related to the vaccine, but it is rare, 2.
Other adverse events associated with vaccination are lymphadenopathy (inflammation or swelling of the lymph nodes), which is a mild side effect that is part of the standard immune response to vaccination, and per 100,000 unvaccinated coronavirus infections There are 78 cases among people, and among vaccinated people, there are only 5 cases per 100,000 people
Compared with the relatively small number of vaccine-related adverse reactions, unvaccinated people with coronavirus infection have a high incidence of serious adverse events, including: arrhythmia (3.
In short, the largest real-world research data on the side effects of the new coronavirus vaccine shows that the BNT162b2 mRNA vaccine has nothing to do with the increased risk of most adverse events, and serious risks such as myocarditis are actually higher in unvaccinated people.
Original source:
Original source:Noam Barda, Noa Dagan, Yatir Ben-Shlomo, et al.
Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting
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