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Neurology: AFFINITY trial: The degree of neurological deficit after stroke increases the risk of depression, and social relationships and cultural background can help reduce the risk

 Last Update: 2022-03-05
 Source: Internet
 Author: User

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In the first year after stroke, 1 in 3 individuals developed clinically significant depressive symptoms
.

Depression is associated with a significant disease burden and may hinder recovery in stroke survivors

post-stroke depression

A recently updated systematic review of factors associated with clinically significant symptoms of post-stroke depression showed that only five studies investigated ≥10 factors, with physical disability being the most consistent risk factor for post-stroke depression
.

New prospective studies have confirmed that the risk of post-stroke depression increases with stroke severity

A secondary exploratory analytical approach study used the Stroke Recovery and Rehabilitation Roundtable Working Group guidelines to define 12 weeks as the early post-stroke period and sought to generate novel and clinically relevant data on the different stages of stroke recovery, i.

A cohort study of 1221 men and women recruited within two weeks of stroke onset in Australia, New Zealand and Vietnam
.

The NiH Stroke Score (NIHSS) is used to assess the severity of stroke

Participants were classified as not depressed, early (first 12 weeks), late (12 to 52 weeks), or persistently depressed (around 12 weeks)

The mean age was 63.
8 years (sd = 12.
3), and the males were 775 years (63.
5%)
.

At baseline, 48 (3.

The severity of neurological and functional deficits increases the risk of clinically apparent early and persistent depressive symptoms after stroke

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