Neurology: Concussion can cause changes in the blood flow and structure of the midline brain structure

Although a concussion is a mild traumatic brain injury (TBI), there is evidence that it has a long-term effect on the physiology of the brain, and its interference will continue until medical clearance (return to play; RTP)

This has raised concerns about whether multiple concussions will have a cumulative effect on the physiology of the brain

However, it is unclear to what extent the effects of repeated concussions can be detected in young, otherwise healthy adults

This study addresses this gap by imaging athletes with and without a history of concussion, from acute injury to one year after RTP, and comparing with a large control group

In this way, Keenan Research Centre for Biomedical Science and others in Canada explored this

Considering the different functional roles and structural connections of these areas, people are also worried about the cumulative effect of damage in these areas

Therefore, the core hypothesis: athletes suffering from concussion have a greater decline in CBF cingulate gyrus, and the interference of FA and MD of the corpus callosum is also greater, and its impact lasts after RTP

In this longitudinal magnetic resonance imaging (MRI) study, 61 uncomplicated concussion athletes (36 HOC patients) were injured in the acute phase (1 to 7 days after injury) and the subacute phase (8 to 14 Days), medical clearance (RTP) to resume the game, imaging performed one month after RTP and one year after RTP

In each course of treatment, the CBF of the cingulate gyrus cortex, as well as the anisotropy (FA) and the average diffusivity (MD) of the corpus callosum are evaluated

They found that athletes with HOC had a larger decrease in the CBF of the middle cingulate in the subacute phase (z=-3.

These effects appear when there is no difference in the SCAT domain (z|<1.

The important significance of this study lies in the discovery: HOC has subacute and chronic effects on the cingulate gyrus CBF and corpus callosum microstructure, but there is no difference in clinical index