Neurology: Eating more fish is good for cardiovascular and cerebrovascular health

Fish is the main source of long-chain-3 polyunsaturated fatty acids (LC n-3 PUFA), and eating fish may help reduce the risk of age-related brain diseases
.

Eating more fish, or increasing the content of n-3 polyunsaturated fatty acids in the blood, is associated with lower cognitive decline, a lower risk of stroke and dementia

Prevent blood vessels

Aline Thomas et al.
hypothesized that fish may have beneficial effects on cerebrovascular health, and studied the relationship between fish intake and the overall burden of cardiovascular disease based on brain MRI markers
.

The research results were published in the journal Neurology

Cardiovascular

The cross-sectional analysis included participants over 65 years of age who had no history of dementia, stroke, or hospitalized cardiovascular disease.
They used brain MRI to automatically assess white matter hyperintensity, visually detect concealed infarctions, and grades of perivascular space dilation
.

The fish intake is assessed by frequency questionnaires, and the main outcome measure is defined as the first component of factor analysis applied to MRI-labeled mixed data

There were 1623 participants (average age 72.
3 years; 63% women)
.

The first component of the factor analysis (32.

The contribution of each MRI phenotype to the cerebrovascular disease burden index

The contribution of each MRI phenotype to the cerebrovascular disease burden index

Higher fish intake is associated with a lower burden of cardiovascular disease
.

The relationship between fish intake and the global burden of cerebrovascular disease

The relationship between fish intake and the global burden of cerebrovascular disease

In the model adjusted for total intracranial volume, compared with participants who ate fish once a week, participants who ate fish 2-3 and 4 times a week β = -0.
19 (95% CI, -0.
37 ;-0.
01) and β = -0.
30 (-0.
57;-0.
03) CVD load indicators were lower (P<0.
001)
.

In the model adjusted for total intracranial volume, compared with participants who ate fish once a week, participants who ate fish 2-3 and 4 times a week β = -0.
19 (95% CI, -0.
37 ;-0.
01) and β = -0.
30 (-0.
57;-0.
03) CVD load indexes were lower (P<0.
001)
.

In the model adjusted for total intracranial volume, compared with participants who ate fish once a week, participants who ate fish 2-3 and 4 times a week β = -0.

The association between fish and cardiovascular disease was stronger in young participants (65-69 years old), but not significant in 75-year old participants

Higher fish intake is associated with lower CVD burden, especially among participants younger than 75 years of age, which suggests a beneficial effect on cerebrovascular health before the emergence of overt brain disease

Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults.

Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults.
Neurology Nov 2021, 10.
1212/WNL.
0000000000012916; DOI: 10.
1212/WNL.
0000000000012916 Fish Intake and MRI Burden of Cerebrovascular Disease in Older Adults.
Neurology Nov 2021, 10.
1212/WNL.
0000000000012916 ; DOI: 10.
1212/WNL.
0000000000012916 leave a message here