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Neurology: Relationship between hypotensive intensity and white matter reticulum integrity in patients with cerebral small vessel disease

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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The diffuse tensor imaging (DTI) network synthesizes damage from multiple pathological processes in cerebral small vessel disease (SVD) and may be a sensitive indicator
of the effectiveness of treatment.

Subjects with lacunar stroke were randomly divided into either the standard blood pressure drop group (systolic blood pressure 130-140 mm Hg), or the enhanced blood pressure drop group (systolic blood pressure = 125 mm Hg) and followed up
with a 2-year MRI at baseline and 2 years.

In trials of cerebrovascular disease, brain network analysis may be a sensitive alternative marker
.

This study provides a second type of evidence that reinforces the reduction of blood pressure in patients with small-vessel disease leading to improved brain network function, when evaluating DDI-based brain network indicators
.

Source: Pflanz CP, Egle MS, O'Brien JT, et al.

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