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Neurology: Relationship between markers of inflammation in middle age and cognitive abilities at 10-year follow-up

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Low levels of inflammation have been linked to many diseases, including cardiovascular disease, obesity, metabolic syndrome, depression, and dementia

Figure 1: Cover art of the paper

It has been suggested that chronic inflammation is promoted by cytokines such as TNF-α and IL-6 excreted from adipose tissue

This prospective cohort study was based on Finland's national, population-based Health Survey 2000, supplementary examinations 2000-2001 and subsequent Health Survey

Baseline low-grade inflammation

915 participants aged 45 to 74 (median age 54 years, 55% were female) were included in the analysis

Figure 2: Graph of the paper results

Elevated IL-6 also predicted a greater decline in VF and WLL after 10 years of follow-up (VF: β: -0.

The study showed that low-grade inflammation in middle age was an independent risk factor for poor cognitive performance later in life

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