Green tea extract may regulate the facial development of children with Down syndrome! Low-dose extract may improve its facial development!

March 20, 2021 // --Recently, a research report entitled "Green tea extracts containing epigallocatechin-3-gallate modulate facial development in Down syndrome" was published in the international journal Scientific Reports , from Belgium and Spain Through research, scientists have found evidence that green tea extract may bring potential health benefits to patients with Down syndrome.

Down syndrome is a congenital hereditary disease induced by an extra chromosome 21.

In this latest study, the researchers analyzed the effect of green tea extract on facial development of patients with Down syndrome.

Image source: KU Leuven

In the study of mice, the researchers started the study before the mice were born (that is, in the mother's womb), adding low-dose or high-dose green tea extract to their drinking water, and found that low-dose green tea The extract may have a positive effect on the Down syndrome mouse model, and 60% of the mice showed a facial morphology similar to that of the control group.

Age-dependent effect

These observational studies were conducted in Spain and also included participants from North America; in the article, the researchers studied a total of 287 participants aged 0-18, including 13 children receiving EGCG supplements.

The researchers said that we did not find similar effects in the adolescent group of subjects.

Further research is needed in the future

Researcher Professor Vande Velde said that although we have observed the potential benefits of green tea extract, considering that these research results are only preliminary studies and are based on observational results, we must handle them with caution; It is necessary to conduct more and more in-depth studies to evaluate the effects of EGCG supplements, its most suitable dosage and overall therapeutic potential; at the same time, researchers also need to consider the effects of EGCG supplements on other organs and systems in the body.

Finally, the researchers stated that the results of this study show that the effect of EGCG strongly depends on its dosage; EGCG products can be obtained through commercialization, and it can also be used as a common body health-promoting compound by people.

Reference materials:

[1] Starbuck, JM, Llambrich, S.