New human genome data set reflects genetic differences among 25 human species

According to the latest issue of "Science" magazine, an international research team sequenced 64 complete human genomes representing 25 human species around the world.

Twenty years ago, the International Human Genome Sequencing Consortium announced the first draft of the human genome reference sequence.

On this basis, scientists have carried out multiple sequencing projects in the past 20 years to identify and classify genetic differences between individuals and reference genomes.

The newly completed reference data set with more comprehensive functions is obtained by combining advanced sequencing and mapping technologies.

The first author of the study, Peter Albert of the Institute of Medical Biostatistics and Bioinformatics, Heinrich Heine University, Germany, said: "With these new reference data, it can be used in the context of global genetic variation.

This research is based on a new method published last year in Nature Biotechnology, which can accurately reconstruct two components of a person’s genome-one inherited from his father and the other from The mother inherited it.