New liquid biopsy technology: a urine test to predict the risk of cancer progression within 5 years

Prostate cancer is one of the most common types of cancer in men, and it usually develops slowly

But not all patients can be such lucky ones, so doctors need to check patients regularly to determine the changes in tumors

According to the latest research published in Life, urine can take on this important task

In previous studies, Dr.

But in fact, there are still some people who fall into the middle "medium risk" group.

The PUR test they designed will analyze a variety of biomarkers, including prostate cancer-specific RNA transcription factors, and prostate cancer-specific genes that contain probes for 36 genes

Based on the levels of these markers in the patient's urine, researchers can classify patients into risk 1-4

Are these two levels relevant before?

The researchers managed to obtain tumor samples from some patients.

For patients whose Gleason classification is still 1-2, their PUR-4 signals are basically the same

Currently, researchers are trying to conduct a larger cohort study to further verify the results

Reference materials:

[1] Prostate cancer urine test identifies good prognosis patients.

[2] Ball, RY, et al.