New Phytologist Li Lei's group discovers a new mechanism for copper homeostasis to regulate ethylene response in Arabidopsis

On July 13, 2022, the research group of Li Lei from the School of Life Sciences and the Joint Center for Life Sciences of Peking University published online in the journal New Phytologist entitled "The carboxy terminal transmembrane domain of SPL7 mediates interaction with RAN1 at the endoplasmic reticulum to regulate ethylene signaling in Arabidopsis" research paper

Copper is an essential trace transition metal in plants and is essential for the biosynthesis and function of ethylene receptors

SPL7 and its homologs are highly conserved regulators of copper homeostasis in green plants with a characteristic SQUAMOSA promoter-binding protein domain (SBP)

Figure 1.

Further immunoprecipitation coupled with mass spectrometry, yeast two-hybrid, luciferase-complementary imaging, and subcellular colocalization analysis revealed that SPL7 interacts with RAN1 on the ER via TMD

Figure 2.

Researcher Li Lei from School of Life Sciences and Life Science Joint Center of Peking University is the corresponding author of the paper, Yang Yanzhi, postdoctoral fellow of Peking University School of Modern Agriculture is the first author of the paper, Hao Chen, postdoctoral fellow of Peking University School of Modern Agriculture, and Du Jianmei, a graduate doctor of the Institute of Frontier Interdisciplinary Research, Peking University Doctoral student Xu Lei also contributed to this paper

Original link: https://nph.