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    Home > Biochemistry News > Microbiology News > New progress has been made in anti-oxidation research of probiotics

    New progress has been made in anti-oxidation research of probiotics

    • Last Update: 2021-08-26
    • Source: Internet
    • Author: User
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    Beijing Academy of Agriculture and Animal Husbandry and Animal Nutrition Laboratory of the well-known international journals in the field of anti-oxidation "Oxidative Medicine forbid Cellular Longevity" ( IF: 6.
    543) Online published a report entitled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activi

    Beijing Academy of Agriculture and the Animal Husbandry The Nutrition Research Laboratory published an online research paper titled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activities in porcine intestinal epithelial cells exposed to hydrogen peroxide" in the internationally renowned journal "Oxidative Medicine forbid Cellular Longevity" (IF: 6.
    543) in the field of antioxidants
    .
    The mechanism of probiotics to alleviate the oxidative stress of porcine intestinal epithelial cells has been studied, which provides a new basis for the analysis of the function of probiotics and their efficient utilization
    .


    Oxidative stress is an important factor in inducing gastrointestinal diseases
    .
    Probiotics can alleviate the intestinal tract Oxidative stress state, but its mechanism of action has not been fully elucidated
    .
    Researchers have established an in vitro porcine intestinal epithelial cell (IPEC-J2) oxidative stress model, and explored the antioxidant mechanism of L.
    plantarum ZLP001
    .
    Studies have found that L.
    plantarum ZLP001 can alleviate the decrease in the activity of IPEC-J2 cells caused by hydrogen peroxide (H2O2), and significantly reduce the apoptosis caused by H2O2
    .
    Compared with H2O2 treatment alone, L.
    plantarum ZLP001 pretreatment reduced the production of reactive oxygen species in cells and the concentration of malondialdehyde MDA, and increased the mitochondrial membrane potential, indicating that L.
    plantarum ZLP001 can promote the maintenance of intracellular redox homeostasis
    .
    In addition, L.
    plantarum ZLP001 can also regulate the expression and production of antioxidant enzymes in the body, thereby activating the body's antioxidant defense system
    .
    L.
    plantarum ZLP001 can cause the enrichment of nuclear factor E2-related factor 2 (Nrf2), and the deletion of the Nrf2 gene significantly weakens the alleviating effect of L.
    plantarum ZLP001 on the oxidative stress of IPEC-J2 cells, indicating that Nrf2 is involved in L.
    plantarum ZLP001 relieves the regulation of oxidative stress in IPEC-J2 cells
    .




     

    Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics.
    com
    .
    The originality and the text and content stated in the article have not been verified by this site.
    This site does not make any guarantee or commitment to the authenticity, completeness, and timeliness of this article, all or part of the content, and the text.
    Readers are invited for reference only, and please Verify the relevant content yourself
    .
     

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    .
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    Media or individuals who do not want to be reprinted can contact us for infringement information that can provide sufficient evidence , Bio149 will be deleted within 12 hours after confirmation
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    3.
    Users are welcome to post original articles to 86371366@qq.
    com, and publish them to the homepage after review.
    The copyright and liability belong to the sender
    .


    Beijing Academy of Agriculture and Animal Husbandry and Animal Nutrition Laboratory of the well-known international journals in the field of anti-oxidation "Oxidative Medicine forbid Cellular Longevity" ( IF: 6.
    543) Online published a report entitled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activi

      Beijing Academy of Agriculture and the Animal Husbandry The Nutrition Research Laboratory published an online research paper titled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activities in porcine intestinal epithelial cells exposed to hydrogen peroxide" in the internationally renowned journal "Oxidative Medicine forbid Cellular Longevity" (IF: 6.
    543) in the field of antioxidants
    .
    The mechanism of probiotics to alleviate the oxidative stress of porcine intestinal epithelial cells has been studied, which provides a new basis for the analysis of the function of probiotics and their efficient utilization
    .


      Oxidative stress is an important factor in inducing gastrointestinal diseases
    .
    Probiotics can alleviate the intestinal tract Oxidative stress state, but its mechanism of action has not been fully elucidated
    .
    Researchers have established an in vitro porcine intestinal epithelial cell (IPEC-J2) oxidative stress model, and explored the antioxidant mechanism of L.
    plantarum ZLP001
    .
    Studies have found that L.
    plantarum ZLP001 can alleviate the decrease in the activity of IPEC-J2 cells caused by hydrogen peroxide (H2O2), and significantly reduce the apoptosis caused by H2O2
    .
    Compared with H2O2 treatment alone, L.
    plantarum ZLP001 pretreatment reduced the production of reactive oxygen species in cells and the concentration of malondialdehyde MDA, and increased the mitochondrial membrane potential, indicating that L.
    plantarum ZLP001 can promote the maintenance of intracellular redox homeostasis
    .
    In addition, L.
    plantarum ZLP001 can also regulate the expression and production of antioxidant enzymes in the body, thereby activating the body's antioxidant defense system
    .
    L.
    plantarum ZLP001 can cause the enrichment of nuclear factor E2-related factor 2 (Nrf2), and the deletion of the Nrf2 gene significantly weakens the alleviating effect of L.
    plantarum ZLP001 on the oxidative stress of IPEC-J2 cells, indicating that Nrf2 is involved in L.
    plantarum ZLP001 relieves the regulation of oxidative stress in IPEC-J2 cells
    .




     

    Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics.
    com
    .
    The originality and the text and content stated in the article have not been verified by this site.
    This site does not make any guarantee or commitment to the authenticity, completeness, and timeliness of this article, all or part of the content, and the text.
    Readers are invited for reference only, and please Verify the relevant content yourself
    .
     

    Copyright notice

    1.
    Some of the reprinted articles on this site are not original, and the copyright and liability belong to the original author
    .
    2.
    All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and clearly indicate the source and author.
    Media or individuals who do not want to be reprinted can contact us for infringement information that can provide sufficient evidence , Bio149 will be deleted within 12 hours after confirmation
    .
    3.
    Users are welcome to post original articles to 86371366@qq.
    com, and publish them to the homepage after review.
    The copyright and liability belong to the sender
    .


    Beijing Academy of Agriculture and Animal Husbandry and Animal Nutrition Laboratory of the well-known international journals in the field of anti-oxidation "Oxidative Medicine forbid Cellular Longevity" ( IF: 6.
    543) Online published a report entitled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activi

      Beijing Academy of Agriculture and the Animal Husbandry The Nutrition Research Laboratory published an online research paper titled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activities in porcine intestinal epithelial cells exposed to hydrogen peroxide" in the internationally renowned journal "Oxidative Medicine forbid Cellular Longevity" (IF: 6.
    543) in the field of antioxidants
    .
    The mechanism of probiotics to alleviate the oxidative stress of porcine intestinal epithelial cells has been studied, which provides a new basis for the analysis of the function of probiotics and their efficient utilization
    .


      Oxidative stress is an important factor in inducing gastrointestinal diseases
    .
    Probiotics can alleviate the intestinal tract Oxidative stress state, but its mechanism of action has not been fully elucidated
    .
    Researchers have established an in vitro porcine intestinal epithelial cell (IPEC-J2) oxidative stress model, and explored the antioxidant mechanism of L.
    plantarum ZLP001
    .
    Studies have found that L.
    plantarum ZLP001 can alleviate the decrease in the activity of IPEC-J2 cells caused by hydrogen peroxide (H2O2), and significantly reduce the apoptosis caused by H2O2
    .
    Compared with H2O2 treatment alone, L.
    plantarum ZLP001 pretreatment reduced the production of reactive oxygen species in cells and the concentration of malondialdehyde MDA, and increased the mitochondrial membrane potential, indicating that L.
    plantarum ZLP001 can promote the maintenance of intracellular redox homeostasis
    .
    In addition, L.
    plantarum ZLP001 can also regulate the expression and production of antioxidant enzymes in the body, thereby activating the body's antioxidant defense system
    .
    L.
    plantarum ZLP001 can cause the enrichment of nuclear factor E2-related factor 2 (Nrf2), and the deletion of the Nrf2 gene significantly weakens the alleviating effect of L.
    plantarum ZLP001 on the oxidative stress of IPEC-J2 cells, indicating that Nrf2 is involved in L.
    plantarum ZLP001 relieves the regulation of oxidative stress in IPEC-J2 cells
    .




     

    Disclaimer: This article only represents the author's personal views and has nothing to do with China Probiotics.
    com
    .
    The originality and the text and content stated in the article have not been verified by this site.
    This site does not make any guarantee or commitment to the authenticity, completeness, and timeliness of this article, all or part of the content, and the text.
    Readers are invited for reference only, and please Verify the relevant content yourself
    .
     

    Copyright notice

    1.
    Some of the reprinted articles on this site are not original, and the copyright and liability belong to the original author
    .
    2.
    All reprinted articles, links and pictures on this website are for the purpose of conveying more information, and clearly indicate the source and author.
    Media or individuals who do not want to be reprinted can contact us for infringement information that can provide sufficient evidence , Bio149 will be deleted within 12 hours after confirmation
    .
    3.
    Users are welcome to post original articles to 86371366@qq.
    com, and publish them to the homepage after review.
    The copyright and liability belong to the sender
    .

    Beijing Academy of Agriculture and Animal Husbandry and Animal Nutrition Laboratory of the well-known international journals in the field of anti-oxidation "Oxidative Medicine forbid Cellular Longevity" ( IF: 6.
    543) Online published a report entitled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activi Beijing Academy of Agriculture and the Animal Husbandry The Nutrition Research Laboratory published an online research paper titled: "Lactobacillus plantarum exhibits antioxidant forbid cytoprotective activities in porcine intestinal epithelial cells exposed to hydrogen peroxide" in the internationally renowned journal "Oxidative Medicine forbid Cellular Longevity" (IF: 6.
    543) in the field of antioxidants
    .
    The mechanism of probiotics to alleviate the oxidative stress of porcine intestinal epithelial cells has been studied, which provides a new basis for the analysis of the function of probiotics and their efficient utilization
    .
    Oxidative stress is an important factor in inducing gastrointestinal diseases
    .
    Probiotics can alleviate the intestinal tract Oxidative stress state, but its mechanism of action has not been fully elucidated
    .
    Researchers have established an in vitro porcine intestinal epithelial cell (IPEC-J2) oxidative stress model, and explored the antioxidant mechanism of L.
    plantarum ZLP001
    .
    Studies have found that L.
    plantarum ZLP001 can alleviate the decrease in the activity of IPEC-J2 cells caused by hydrogen peroxide (H2O2), and significantly reduce the apoptosis caused by H2O2
    .
    Compared with H2O2 treatment alone, L.
    plantarum ZLP001 pretreatment reduced the production of reactive oxygen species in cells and the concentration of malondialdehyde MDA, and increased the mitochondrial membrane potential, indicating that L.
    plantarum ZLP001 can promote the maintenance of intracellular redox homeostasis
    .
    In addition, L.
    plantarum ZLP001 can also regulate the expression and production of antioxidant enzymes in the body, thereby activating the body's antioxidant defense system
    .
    L.
    plantarum ZLP001 can cause the enrichment of nuclear factor E2-related factor 2 (Nrf2), and the deletion of the Nrf2 gene significantly weakens the alleviating effect of L.
    plantarum ZLP001 on the oxidative stress of IPEC-J2 cells, indicating that Nrf2 is involved in L.
    plantarum ZLP001 relieves the regulation of oxidative stress in IPEC-J2 cells
    .

     
     
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