-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
| New study assesses the safety and efficacy of Modena vaccine booster |
Science and Technology Daily, Beijing, September 23 (Reporter Zhang Mengran) A vaccination study carried out on 80 people showed that Modena's mRNA-1273 vaccine and the modified vaccine against the variant strain are safe and well tolerated as a booster.
And it can increase the level of neutralizing antibodies against the new coronavirus "mutant strains" (including beta, gamma, and delta variants)
.
This result was published in the recent "Nature Medicine" as an interim analysis of an ongoing clinical trial
With the emergence of new coronavirus "mutant strains" and "mutant strains" and the weakening of the neutralizing effect of antibodies, people began to pay more attention to booster injections and vaccines against variant strains
.
In order to evaluate the safety and efficacy of the new coronavirus booster shot, the researchers asked subjects who had received two injections of Modena vaccine (mRNA-1273) to receive a booster shot 6 months later
American Modena researcher Darling Edward and his colleagues observed four booster injection groups this time (20 subjects in each group, and the injection vaccine was a different combination of original and modified vaccines)
.
Immediately before the booster shot, the level of neutralizing antibodies against the new coronavirus in the blood of the subjects was lower than their level one month after the second shot, and they were targeted at the “mutant strains that need attention” Beta, Gamma, and Delta.
The research team found that the three booster injections they tested can make the subjects' new coronavirus neutralizing antibody titers higher than the level one month after the first round of vaccines, especially the increase caused by mRNA-1273 and mRNA-1273.
211 Significantly
.
In addition, all three booster shots can increase the neutralizing antibody titers against beta, gamma, delta variants, and other variants that need attention
The researchers acknowledged that the preliminary analysis still has some limitations, including the small sample size and the fact that the treatment groups on which the results are based were not randomly assigned
.
However, they believe that the trial's mRNA technology platform for testing of mutant strains of the new coronavirus that needs attention seems to be effective in strengthening needle research and development
Focus on the new crown pneumonia epidemic
