Non-nutritive sweeteners alter the human microbiome

In the past two years, with the increasing incidence of chronic diseases in China and the popularization of health knowledge, more and more foods or beverages have replaced the original sucrose, fructose, etc.

As early as 2014, the research group conducted animal experiments to verify the effect
of NNS on the microbiome in mice.

The results showed that some NNS affected the participants' blood sugar profile
.

What are the deep causes of NNS affecting metabolic changes such as blood sugar in the human body? Based on previous models of animal experiments, the researchers set their sights on the microbiome in the human body
.

In the past, people called these sweeteners "non-nutritious", in large part because they were considered inert and had no effect on
the human body.

When the researchers transferred the microorganisms in the NNS group participants to sterile mice, the blood glucose changes in these mice were very similar to those in the donor's blood sugar changes, and the mice in the saccharin group and surose group had more significant blood glucose level fluctuations, significantly higher than in the control group; The blood glucose changes in mice in the aspartame and stevia groups were almost identical
to those in the control group.

However, the researchers also emphasize that the effects of NNS on the human microbiome are highly "personalized", and the damage to blood sugar changes also varies from person to person
.

Research suggests that NNS is not as inert as people first recognize, but can have a highly personalized effect on
human physiology.

Corresponding author Eran Elinav said that people's desire for sweets is pushing scientists to find healthier alternatives, but in the personal view, drinking white water may be the most effective and healthy solution
.

(Source: Mace Medicine)

China Food News(2022.

(Editor-in-charge: Han Songyan)