Oncotarget: Microbiome disorders lead to breast cancer.

9, 2017 /BIOON/ -- In a recently published article, researchers from Cleveland Clinic found differences in the composition of bacteria in the breast tissues of healthy women and women with breast cancer.
they found for the first time that healthy women's breast tissue contains more methyl bacteria.
the results may offer new ideas for breast cancer treatment.
microorganisms that live in the body, also known as the microbiome, have an important impact on the occurrence of many diseases in the body.
previous studies have focused on gut microbes, the microbes that are present in the digestive tract.
long ago, researchers agreed that microbiomes also exist in breast tissue and play a key role in the development of breast cancer, but the specific microbial composition and how it works has not been analyzed.
, the researchers developed a preliminary understanding of the relationship between differences in microbial composition and cancerous breast tissue by comparing the composition of microorganisms in healthy breast tissue to cancerous breast tissue.
results were published in the latest issue of Oncotarget.
the study, the authors collected breast cancerous tissue left behind by 78 patients after undergoing surgery, and also tested microbial composition in different parts of the patient (urine, oral secretion).
addition to methyl methyl bacteria, the authors found higher levels of Granizer-positive bacteria in the urine of cancer patients, including staphylococcus aureus and line bacteria.
that follow-up studies are needed to determine whether these bacteria have an effect on breast cancer.
breast cancer is the second-highest risk type of cancer in the U.S. female population (the first is skin cancer), with one in eight women at risk of developing breast cancer in their lifetime.
the study provides conceptual evidence that there are microbial components that promote breast cancer, thus providing new potential for breast cancer prevention and treatment.
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