echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > One drug has the potential to curb multiple cancers

    One drug has the potential to curb multiple cancers

    • Last Update: 2021-11-12
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com


    UTSW finds RAS inhibitors can be used to fight more cancers

    Source: University of Texas Southwestern Medical Center

    The new findings of researchers at the University of Texas Southwestern University help to better understand how the most common cancer gene mutations signal the cause of cancer


    The research, published in the journal Nature Structural & Molecular Biology, focuses on a family of proteins called RAS, which is used in all cancers, especially fatal cancers such as pancreatic cancer and colon.


    "A framework for developing RAS inhibitor strategies is urgently needed, because recently approved RAS inhibitors, such as sotorasib, are only effective against one specific mutation, and many other RAS mutations can also cause cancer," one of the authors of the study, Said Dr.


    Beginning in 2012, Dr.


    "Cysteine ​​is a unique amino acid that allows us to use special chemicals to attach drugs irreversibly


    The work of his laboratory drove the approval of the KRAS G12C inhibitor sotorasib in May


    In the latest research, Westover's laboratory is trying to understand how the oncogenic RAS mutant transmits inappropriate signals from the cell surface to the nucleus


    "This structural model is now available for wider RAS research," said Dr.


    Since the RAS signal depends on the formation of the RAS complex, Dr.



    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.