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1.
Werner established the theory of coordination chemistry.
The structure determines the properties.
2.
Conjugated organic frameworks (COFs) are a class of crystalline organic porous materials made up of organic structural units connected by covalent bonds.
Although the first single crystal of COFs has been synthesized by Ma Tianqiong and provides an effective strategy for synthesizing COF single crystal, the synthesis of this single crystal takes a lot of time, and at the same time, different specific and effective adjustments need to be found for different COFs.
3.
In the study of MOFs/COFs, the slowest step is often to determine the structure of the product.
MicroED stands for Microcrystalline Electron Diffraction.
Below we introduce several examples of structure analysis of MOFs and COFs through MicroED.
Case number one
Used by Sun Junliang Research Group of Peking University and its collaboratorsThe cRED (equivalent to MicroED) technology collects electron diffraction data for a two-dimensional conductive MOF with a size of 5-10 μm—Cu3HHTT2, and obtains data with a resolution of 1.
Figure 1 (a) (b) Schematic diagram of the structure of Cu3HHTT2 (c) (d) Cu3HHTT2 morphology and its three-dimensional reciprocal lattice
Case two
The Xiaodong Zou research group of Stockholm University and its collaborators have analyzed the structure of the photochemically active MOFs—PCN-415 and PCN-416.
Figure 2 (a) (b) PCN-415 and PCN-416 3D reciprocal lattice reconstruction from cRED data; (c) (d) Rietveld refinement of PCN-415 and PCN-416 PXRD; (e) ) Schematic diagram of the structure of PCN-415; (f) Schematic diagram of the fcu topology of PCN-415
Case three
Xiaodon Zou’s research group also synthesized a new type of porous cobalt MOF—Co-CAU-36.
Figure 3 (a) Three-dimensional reciprocal lattice (b) structure diagram of Co-CAU-36
Case Four:
Peking University's Sun Junliang research group and Wuhan University Wang Cheng's research group cooperated to obtain the 3D-TPB series COF structure through MicroED (Figure 4-5).
Figure 4 The morphology of 3D-TPB-COF and its three-dimensional reciprocal grid
Figure 5 Schematic diagram of the structure of 3D-TPB-COF
to sum up
Single crystal X-ray diffraction is the main method for structural analysis of MOFs and COFs, but only large-sized single crystal samples can be tested.
Qingyun Ruijing is good at MicroED microcrystalline electron diffraction technology, and has its own world-leading MicroED test platform, which can quickly and accurately analyze the structure of nanocrystals.
It can obtain structural information without a long single crystal culture process, which is a scientific research and academic field.
Provide technical support.
In addition, MicroED can further test materials such as proteins, peptides, and small drug molecules.
It can obtain structural information without a long single crystal culture process, which is a scientific research and academic field.
Provide technical support.
In addition, MicroED can further test materials such as proteins, peptides, and small drug molecules.
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