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Peptoids and PeptidePeptoid Hybrid Biopolymers as Peptidomimetics

 Last Update: 2020-12-20
 Source: Internet
 Author: User

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Peptoids (oligomers of
N
-substituted glycine residues) and peptide–peptoid hybrid polymers (peptomers) are interesting classes of compounds mimickingstructure and function of biologically active peptides. The oligomeric peptidomimetics such as peptoids are particularly importantcompounds since they provide access to an enormous molecular diversity, by variation of the building blocks. The modular structureof peptoids, ease of synthesis, and high compatibility with existing peptide chemistry synthetic protocols, make peptoidsand peptoid-containing peptidomimetics ideal tools for structure–activity and drug discovery related studies.

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