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Phage Replication Technology for Diagnosis and Drug Susceptibility Testing

 Last Update: 2021-02-18
 Source: Internet
 Author: User

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Of the world’s infectious diseases, tuberculosis remains the leading cause of mortality and it has been estimated that of the eight million new cases that occur each year 95% are found in the less developed countries (
1
,
2
). Diagnostic methods that involve culture of
Mycobacterium tuberculosis
are necessarily slow due to the protracted growth times required by these bacteria. Rapid molecular tests have been developed for both diagnosis (
3
) and drug resistance testing (
4
). However, the high costs and requirement for specialized equipment prohibits the routine application of this technology in low-income countries, and there is an urgent need for sensitive, rapid tests that are affordable and appropriate for use in these areas of the world (
5
).

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