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    Home > Active Ingredient News > Drugs Articles > Pharmaceutical grade polysorbate 80 tween 80cas9005-65-6 uses

    Pharmaceutical grade polysorbate 80 tween 80cas9005-65-6 uses

    • Last Update: 2022-08-20
    • Source: Internet
    • Author: User
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     Pharmaceutical grade polysorbate 80 Tween 80cas9005-65-6 Uses This product is a light yellow to orange yellow viscous liquid; it has a slight odor
    .

    The taste is slightly bitter and astringent, with a warm feeling
    .

    Soluble in water, ethanol, methanol or ethyl acetate, very slightly soluble in mineral oil
    .

    A type of surfactant commonly used in liquid formulations
    .

    It is an oil/water emulsifier and can be used as stabilizer, diffusing agent, antistatic agent, fiber lubricant,
    etc.

    By the reaction of sorbitan monooleate and ethylene oxide
    .

    Polysorbate 80 (or Tween 80) is an organic substance with a chemical formula of C64H124O26.
    It is a non-ionic surfactant with an odor, warm and slightly bitter
    .

    It is one of the polyoxyethylene sorbitan fatty acid ester series products
    .

    【Properties】This product is light yellow to orange-yellow viscous liquid
    .

    This product is easily soluble in water, ethanol, methanol or ethyl acetate, and very slightly soluble in mineral oil
    .

    Relative density The relative density of this product (general rule 0601) is 1.
    06 to 1.
    09
    .

    Viscosity The kinematic viscosity of this product (the first method of general rule 0633) is 350~550mm2/s at 25°C (the inner diameter of the capillary is 2.
    0~2.
    5mm)
    .

    Take 10g of this product for acid value, accurately weigh it, put it in a 250ml conical flask, add 50ml of neutral ethanol (neutral to phenolphthalein indicator solution) to dissolve, attach a reflux condenser to boil for 10 minutes, let it cool, add phenolphthalein indicator solution 5 drops, titrated with sodium hydroxide titration solution (0.
    1mol/L), the acid value (general rule 0713) should not exceed 2.
    0
    .

    Hydroxyl Value The hydroxyl value of this product (general rule 0713) is 65-80
    .

    Iodine value The iodine value of this product (general rule 0713) is 18 to 24
    .

    Peroxide value The peroxide value of this product (general rule 0713) shall not exceed 10
    .

    Saponification value The saponification value (general rule 0713) of this product is 45-55
    .

      [Identification] (1) Take 5ml of the aqueous solution (l→20) of this product, add 5ml of sodium hydroxide test solution, boil for several minutes, let it cool, and acidify with dilute hydrochloric acid, showing milky white turbidity
    .

      (2) Take the aqueous solution of this product (1→20), add bromine test solution dropwise, the bromine test solution will fade
    .

      (3) Take 6ml of this product, add 4ml of water and mix well, it will be a jelly
    .

      (4) Take 10ml of the aqueous solution (1→20) of this product, add 5ml of cobalt ammonium thiocyanate solution (take 17.
    4g of ammonium thiocyanate and 2.
    8g of cobalt nitrate, add water to dissolve into 100ml), mix well, add 5ml, Shake to mix, and after standing, the layer turns blue
    .

    Sodium acetate (anhydrous trihydrate) CAS No.
    : 6131-90-4 Colorless and odorless crystals, can be weathered in the air
    .

    Soluble in water and B M, slightly soluble in ethanol
    .

    Citric acid Citric acid anhydrous monohydrate CAS number: 77-92-9 White translucent crystal or powder
    .

    Soluble in water and ethanol, soluble in ethyl M hydrogenated castor oil CAS No.
    [8001-78-3] Appearance: white to light yellow powder, block or flake
    .

    Potassium bicarbonate CAS No.
    : 298-14-6 Potassium bicarbonate is a white solid belonging to the inorganic compound Microcrystalline Cellulose CAS No.
    : 9004-34-6 Insoluble in water, dilute acid and almost all organic solvents
    .

    Slightly soluble in sodium hydroxide solution and hot sodium casein solution
    .

    Sodium Lauryl Sulfate CAS No.
    : 151-21-3 Easily soluble in water, slightly soluble in ethanol, almost insoluble in L-form, B M polyvinyl alcohol CAS No.
    [9002-89-5] White to slightly yellow powder or Translucent particles; odorless, tasteless 
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