Pharmacological effects and clinical application of black ants.

The small silt black ant is the dry body of insect winged winged ants, which is mainly produced in Guizhou, Yunnan, Guangxi and other places, and was identified by the Ministry of Health of China in 1993 as the only two-use good ant species.
"Herb Outline" records: "Ants, the release of the name of Xuanxuan, but also ants ... Ant force is the largest, can lift equal body iron, human food can benefit the strength", with the positive solid book, the network, the effect of complementing the kidney strong yang.
Modern clinical use of black ants for the treatment of rheumatoid and rheumatoid arthritis, hepatitis B, diabetes, relapsed staphylococcitis and shoulder inflammation and other diseases, has a high medicinal value, known as "micro animal nutrition treasure trove" and "natural drug processing plant."
Ants contain more than 70 nutrients needed by the human body, including protein and amino acids rich in protein content of up to 42%-67%, containing 9 enzymes and coenzymes, 28 kinds of free amino acids, growth hormone, interferon and 8 essential amino acids of the human body.
Ants also contain high-energy phosphorus-containing compounds adenosine triphosphate (ATP) and ant aldehydes, antic acid, etc., containing a variety of trace elements necessary for the human body selenium, manganese, zinc, phosphorus, calcium and other minerals, of which 14 are required by the human body, especially zinc, selenium content is the most abundant, zinc content per 1 kg of ants up to 230 to 280 mg.
ants also contain ant aldehyde, chest ant aldehyde, lemon aldehyde and other special compounds, as well as a variety of alkaloids and vitamins B1, B2, B12, A, C, D, E and other vitamins.
these components make up the black ant anti-rheumatoid, anti-inflammatory, liver care, analgesia, tumor suppression material basis, ants high zinc can treat severe zinc deficiency, rheumatoid arthritis.
the pharmacological effect of black ants1, enhanced immunity studies show that black ant powder can significantly improve the lymphocyte conversion capacity of mice, the number of antibody-producing cells and natural killer cell activity, thereby enhancing the immune function of mice.
In addition, black ant ethanol extract can significantly improve the phagocytosis rate, the number of empty spot formation cells, T lymphocyte proliferation rate and leukocyte interleton 2 (IL-2) level, enhance the immune function of mice with low immune function liver cancer model.
addition, black ants have obvious recovery and protection effect on the immune function damage caused by cyclophosphamide, which can promote the production of antibodies of B lymphocytes in outer blood and enhance the immune function of mice.
2, anti-inflammatory analgesic-related research found that compound black ant capsules (composed of black ants, hemp, 37, paracetam and other drugs) can significantly inhibit the primary and secondary inflammation of rats caused by complete Fleur admissions, reducing the number of acetic acid-caused mouse twists.
Compound ant wine can significantly improve the early inflammation of complete admissive arthritis in rats, and significantly inhibit the inflammation of the ear profile in mice caused by secondary morbidity and xylene, as well as the painful and acetic acid-torsional reaction in mice.
3. The petroleum ether site of anti-aging black ant alcohol can improve the content of glutathione (GSH) in the serum of subacute aging model mice, and soD activity in hippocemia and cerebral cortical tissue.
studies have shown that injections of black ant hydrodynamic fluid can play an anti-aging role by increasing THED, RNA content and maternal cell rate in the outer lymphocytes of mice and increasing the content of Mn, Se, and Zn in the blood and immune organs of older mice.
4. The regulated blood sugar black ants had a significant hypoglycemia-lowering effect on diabetic model mice caused by oxyxyxine, and had a quantum effect on the dose, but had no significant effect on blood sugar in normal mice.
Black Ant Ethanol Extract can significantly improve the sugar tolerance of genetic KKAy type 2 diabetes model mice, and 50% and 95% of ethanol extract can significantly improve the sugar tolerance of NIH mice and Kunming mice of different sexes, indicating that their ethanol extract may be an effective site to improve sugar metabolism.
5, renal strong yang ants clear wine (including black ants, mussels, hazelnuts and other 12 flavor Chinese medicine) can significantly increase the semen sac, prostate and foreskin quality of descending male mice, normal male mice testicular and testicular mass and sperm number, as well as the testicle and thymus quality of older male mice.
black ant powder had a certain renal effect on impotence model mice and desotrophic male rats caused by high doses of corticosteroids.
6, antidepressant black ant alcohol to blood-level-induced depression model rats have a significant antidepressant effect, the mechanism of action and regulation of neurotransmitter metabolism and anti-nerve cell oxidation.
Other studies have found that the black ant petroleum ether site can significantly improve the depressive behavior of rats, inhibit the expression of nuclear transcription factor KB (NF-KB) pathline protein, reduce the pre-cortical inflammation factor IL-1 beta and tumor necrotic cause, inhibit the activation of small glial cells and astrocytes in depressed model rats, and the expression level of the pyridine 2,3-dioxygenase gene.
7, other effects of ant alcohol leaching paste and ant preparations (black ants as a medicine, coupled with raw jaundice, jaundice, dansin and other Chinese medicine made of compound preparations) on carbon tetrachloride caused by rat liver damage It has protective effect, and can reduce the activity of alanine amino transferase and mendonine amino transferase, reduce the fatty degeneration and necrosis of liver cells, slow the growth of liver fiber tissue, and promote the synthesis of chronic liver damage albumin and serum total protein.
black ant alcohol can significantly extend the weight of mice swimming time, reduce the area under the blood lactic acid curve, speed up the removal of lactic acid, reduce the content of urea nitrogen in the serum, indicating that it has anti-motor fatigue.
black ants have unique therapeutic effects in clinical applications, especially in the treatment of rheumatoid and rheumatoid arthritis, hepatitis B and diabetes.
found that compound black ant capsules (the main components are black ants) have obvious effects on waist and leg weakness, decreased sexual function, insomnia, scissor nerve pain, and low immune function.
The tian ant steroid particles made from groups such as black ants, jaundice and hive spleen extract treat hepatitis B patients of different types (acute, chronic, cirrhosis) and set up control groups (treated by traditional methods).
results show that the tempellet particles have obvious therapeutic effects on different types of hepatitis B.
There are studies to ants as a medicine, with ginseng, jaundice, raw land and other yin-replenishing, raw and dry Chinese medicine made of ants sugar dispersion, used in the treatment of type 1 diabetes, type 2 diabetes patients have achieved good results.
Black ant chemical composition is rich, the main components are dopamine derivatives, alkaloids, organic acids, amino acids and other components, its pharmacological activity is significant, with enhanced immunity, anti-inflammatory analgesia, anti-aging and other pharmacological effects, in clinical applications also has a unique efficacy, especially in the treatment of rheumatoid arthritis, hepatitis B and diabetes and other important efficacy.
black ant-related preparations currently used in clinical clinics are still few, so it is possible to develop innovative drug forms.
, the specific material basis of the pharmacological activity of black ants is still not yet discovered, and further research is needed.
references: Yang Zhixin, Liu Hui, Xu Guijun, Qi Lili, Yu Shijia, Lu Weiwa. Advances in chemical composition, pharmacological effects, and clinical application of black ants . . . Chinese Pharmacy, 2020, 31 (09): 1148-1152. Lu Kizong, Van Heart. Black Ant Nutrition Treasure. China Health Nutrition, 2011 (02): 58-59. Introduction to the author: Small silt, food science and technology workers, graduated from the South China University of Technology School of Food Science and Engineering, Master of Food Science, is now working in a large domestic pharmaceutical research and development company, engaged in the development and research of nutritious food.
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