Science and Technology Daily (Reporter Zhao Hanbin) Pluripotent stem cells are the basis of individual development and one of the important seed cells for regenerative medicine
Due to the special developmental status, the pluripotent stem cell genome has a high degree of homeostasis
Zheng Ping's research group from Kunming Institute of Zoology has long-term research on the characteristics of pluripotent stem cell genome homeostasis and unique regulatory mechanisms
Because long-chain non-coding ribonucleic acid can effectively increase the concentration of protein factors through phase change, thereby significantly improving work efficiency
The researchers also constructed gene knockout mice and found that the species-conserved long-chain non-coding ribonucleic acid gene knockout can lead to neonatal death and neurodevelopmental abnormalities.
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