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Positive clustering, "big flu", human-to-human transmission... These 11 hot topics, the latest interpretation of senior infectious disease expert Lu Hongzhou

 Last Update: 2022-05-16
 Source: Internet
 Author: User

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What's going on with "positive pilgrimage"? Will the toxicity of the new crown virus become weaker and weaker? Bill Gates once thought that Omicron was a "natural vaccine", is this view correct, and what is the risk of the sequelae of the new crown

Regarding these popular questions, on the evening of April 11, Lu Hongzhou, president of Shenzhen Third People's Hospital and academician of the American Academy of Microbiology, was invited to the live broadcast room of "Deep Study of Science" to conduct a professional interpretation and give his own answers

Professor Lu Hongzhou is currently the dean of the Shenzhen Third Hospital.

Q: Some experts believe that the mutation direction of the new coronavirus is that the speed of transmission is getting faster and the symptoms are getting milder.

Lu Hongzhou

The same is true for Omicron.

Q : Recently, the topic of "positive pilgrimage" has attracted much attention.

Q Recently, the topic of "positive pilgrimage" has attracted much attention.

Lu Hongzhou

Q : Some people think that Omicron is the "big flu".

Q : Some people think that Omicron is the "big flu", is this statement reliable?

Lu Hongzhou : This year, due to the epidemic, especially the epidemic in Hong Kong, the overall number of cases and deaths in China has increased extremely rapidly.

Lu Hongzhou

Globally, 3,900 people die every day from the new crown, so let's not call the new crown / Omicron the "big flu"

In our country, there are more than 50 million cancer patients and elderly people (editor's note: elderly people with various underlying diseases)

The total number of confirmed cases of new crown in the world and the number of confirmed cases in China

Global COVID-19 Deaths vs.

Q: Based on the current situation of repeated epidemics and mild symptoms of Omicron, Bill Gates once pointed out that "Omicron is a natural vaccine".

Lu Hongzhou:

First of all, Omicron ≠ "big flu"
.
This is because countries such as Europe and the United Kingdom still have a large number of deaths every day during the epidemic of Omikron, and the number of people who die every day due to Omikron in the world exceeds 1,000
.
It still kills a lot of people, so it shouldn't be called the "big flu
.
"

Secondly, if the virus is allowed to spread among people, it will continue to mutate, and it may also recombine with the virus in animals (Note: 26 kinds of animals are known to have detected the new coronavirus), so that it will be a virus for the virus opportunities for increased infectivity
.

So I don't agree with the view that "Omicron is a natural vaccine"
.
The best way for us to prevent or control the epidemic now is not to let the virus spread widely among people, otherwise a highly pathogenic virus will appear
.
At present, several major epidemic strains are from countries with severe epidemics.
For example, the Delta strain was first discovered in India, and the Omicron strain was first discovered in South Africa
.

Q: What are the differences between asymptomatic, mild and severe patients in the sequelae of the new crown?

Lu Hongzhou: The sequelae of the new crown are actually not that serious
.
We have followed up patients with the new crown after the outbreak, and have done relevant research on the neurological aspects and brain atrophy of the patients.
At present, we have found that no serious sequelae have been found, so I don’t think it is too exaggerated to exaggerate the sequelae of the new crown.
Most people are fully recoverable
.

Lu Hongzhou:

Q: Do you have any good advice to prevent the spread of the new coronavirus through contact, such as human-to-human transmission?

Lu Hongzhou: The spread of the virus is mainly through the respiratory tract, that is, the close contact between people leads to the spread of the virus
.

Lu Hongzhou:

The second is the contact of items, such as express delivery and cold chain, but the probability of such transmission is still relatively low
.
If the virus is in the cold chain, it is equivalent to being stored in a large refrigerator, and the virus can survive for a long time
.
The survival time of the virus on the surface of different items and the amount of virus transmitted to humans are all mechanisms of human-to-human transmission
.

We are conducting a study to simulate the conditions required for human-to-human transmission on different surfaces, at different temperatures, and in constant or micro quantities
.
The results of this study will provide a very good scientific basis for the prevention and control and basic measures of human-to-human transmission in the future, and will also provide better suggestions on disinfection methods to prevent human-to-human transmission
.

Q: Does nasal irrigation help protect against the new coronavirus?

Lu Hongzhou: We made a very simple popular science video on the Internet before, telling everyone how to perform nasal irrigation
.
Because the virus is mainly concentrated in the upper respiratory tract and nasopharynx, nasal irrigation with weakly irritating disinfectants (such as sea salt water, physiological saline, iodine-containing disinfectant, etc.
) can effectively play a role in disinfection
.

Lu Hongzhou:

After nasal irrigation, the amount of virus will be greatly reduced
.
We have done relevant research.
After simply rinsing the nasal cavity, the time of the first transfer of the virus is five days earlier, and after the nasal cavity virus is transferred, the patient is no longer infectious and can be discharged soon
.
This method of nasal irrigation is inexpensive, practical, easy to operate, and very effective
.

U.
S.
pregnant women with new crown infections and deaths

U.
S.
child infections and deaths

Q: Are pregnant women and children at great risk from the new coronavirus?

Lu Hongzhou: In the United States, the number of pregnant women who have died from the new coronavirus is 282
.
Even if we think Omicron has mild symptoms, there are a lot of pregnant women dying during this wave of Omicron epidemics, so we can't take it lightly
.
The same goes for children, with 66 children dying due to multisystem inflammatory response syndrome
.
In the past, we thought that children infected with the new coronavirus had mild symptoms, but in the United States, we found that some children will become seriously ill and die
.

Lu Hongzhou:

In general, children under the age of three who have not been vaccinated have severe symptoms after infection, but their symptoms are generally milder after receiving three doses of the vaccine
.
So children also need to be vaccinated
.

Q: What is the effect of mRNA vaccine? What new vaccines will be needed in the future?

Lu Hongzhou: The United States, the United Kingdom and other countries use mRNA vaccines, but after they received three injections and opened them one after another, a large number of people were still infected, so even mRNA vaccines still cannot completely prevent the spread of the virus and the emergence of severe diseases, especially for For some people who have underlying diseases or who cannot produce the corresponding comprehensive antibodies
.

Lu Hongzhou:

At present, although mRNA vaccines are effective, they are not the most ideal vaccines.
In the future vaccines, inhaled vaccines for the respiratory tract will be developed
.
If all the epithelial cells in our respiratory tract have corresponding cellular immunity, and the cellular mucosa also has mucosal immunity, then this vaccine is a real preventive vaccine
.

But our current technology has not yet reached this point, so in the future we need to develop this vaccine in order to generate broad herd immunity in the population
.

Q: Can UV light be used indoors to effectively eliminate the new coronavirus?

Lu Hongzhou: The best way to disinfect indoors is to open windows for ventilation
.
However, for some viruses on the surface of the items, we can disinfect them with chlorine-containing disinfectant or ultraviolet rays.
It is very easy to be inactivated, that is, the viruses can be inactivated by ordinary disinfection methods
.

Lu Hongzhou:

In addition, if a room is not used, the virus in this room will be inactivated naturally
.
Because the in vitro survival time of the virus is relatively short, about a day or so
.

Q: The Ebola virus only needs one virus to infect, and the influenza virus needs 1,000 viruses.
How many viruses are needed to infect the new crown?

Lu Hongzhou: I am currently doing related research on this issue.
We have not yet come to a corresponding conclusion as to how many viruses are contagious, under what conditions, and under the temperature environment
.
In the future, we will have a more definite conclusion, and we will tell you at that time
.

Guest profile

Lu Hongzhou is currently the President of Shenzhen No.
3 Academy of Sciences, the head of the Shenzhen Public Health Expert Group on Epidemic Prevention and Control, and an academician of the American Academy of Microbiology.

Doctor of internal medicine, postdoctoral fellow in the United States, chief physician, second-level professor; doctoral tutor of internal medicine, public health management and nursing
.
He used to be secretary of the Party Committee of Shanghai (Affiliated to Fudan University) Public Health Clinical Center and assistant to the president of Huashan Hospital Affiliated to Fudan University
.
Director of the World Health Organization's Collaborative Center for Clinical Diagnosis and Treatment of Emerging Infectious Diseases; a member of the rear support team of the National New Coronary Virus Disease Treatment Expert Group and the Overseas Anti-epidemic Expert Group
.
Former chairman of the Tropical Diseases and Parasites Branch of the Chinese Medical Association and head of the AIDS group; vice president of the China Association for the Prevention and Treatment of STDs and AIDS and head of the tuberculosis group; director of the Infectious Diseases Branch of the European and American Students Association (Chinese Overseas Students Association) Medical Association Member; Deputy Head of the AIDS Professional Group of the Infectious Diseases Branch of the Chinese Medical Association; Chairman of the Infectious Diseases Branch of the Shanghai Medical Association; Member of the National Expert Committee for Disease Control and Prevention; Shanghai (Avian) Influenza, Ebola, Yellow Fever , Head of the clinical expert group for Zika virus disease treatment; experts from the National Health Commission AIDS, Influenza, Ebola Virus Disease, Infectious Diseases Quality Control Center
.

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