Probiotics regulate gut microorganisms to relieve mental anxiety during crew sailing

china's maritime land area of nearly 3 million square kilometers. Compared with the land environment, the marine environment has high humidity, high salinity and strong ultraviolet radiation. The long-distance crew not only face the monotonous environment, but also have problems such as circadian rhythm disorder and lack of sleep. In addition, due to the limited supply period of fresh fruits and vegetables, sea-going personnel are more likely to produce greater physical and psychological stress. In recent years, gastrointestinal disorders and mental health problems of long-term seafaring crews have become increasingly prominent, and it is imperative to improve the physical and mental health of seafarers by eating probiotics.82 ocean-going crew members were recruited for this study. During the 30-day sailing mission, 40 seafarers took mixed probiotic products (species include: Cheese Lactobacillus Zhang, Plant Lactobacillus P-8, Lactobacillus C. The results showed that after the voyage, 42 seafarers who took placebo had intestinal bacteri group disorders, increased levels of pathogenic bacteria (Gordon's Streptococcus and Pneumonia Kreber), and the crew's psychological stress and mental anxiety were at risk. In contrast, 40 seafarers who continued to take probiotics maintained a steady state of intestinal bacterial composition and bacterial function genes during the voyage, and their stress and mental anxiety conditions were significantly reduced. Based on the correlation analysis of crew mental state index and intestinal microbiome, it is shown that compound probiotics can effectively regulate the crew's intestinal microorganisms, and beneficial bacterial group metabolites can improve the mental anxiety of distant crew members by acting on the host nervous system through the intestinal-brain axis. The results of this research provide an effective solution for maintaining the intestinal micro-ecological health of the voyage crew and alleviating the mental anxiety of the crew during sailing, and provide a new perspective for the personalized selection of probiotics.study, "Probiotics maintain the intestinal microbiome homeostasis of the sailors when a long sea voyage" was published online in February 2020 by researchers from the Key Laboratory of the Ministry of Dairy Biotechnology and Engineering of Inner Mongolia Agricultural University in the journal Gut Microbes (Impact Factor: 7.74).original link: