Professor Zhang Shiqian: Endometrial cancer chemotherapy is a double-edged sword, use or not?

Endometrial cancer is one of the common malignant tumors of the female reproductive tract.
The clinical treatment principle is based on surgery, supplemented by comprehensive treatments such as radiotherapy, chemotherapy and hormone therapy
.

Chemotherapy is the abbreviation of chemotherapy.

Endometrial cancer is one of the common malignant tumors of the female reproductive tract.

1.

Professor Zhang Shiqian: Blood Vessel

For different academic organizations, the treatment guidelines for high-risk endometrial cancer in the first phase are almost the same, but there is little difference in whether to use chemotherapy, but specific to the clinical work, it is necessary to consider the tumor is a systemic disease.
Some studies are correct Some patients with stage I endometrial cancer find that there are cancer cells in the circulation when they do peripheral ctDNA.
Therefore, whether to use chemotherapy for middle- and high-risk patients in stage I requires further clinical trials
.

As far as the current situation is concerned, mainstream guidelines recommend no chemotherapy, but there are still individual organizations recommending it, which reflects the uncertainty of medicine

2.
Choice of chemotherapy drugs

2.
Choice of chemotherapy drugs

Professor Zhang Shiqian: The Japanese guidelines recommend the use of platinum combined with adriamycin, platinum combined with paclitaxel, and even combined with chemotherapy drugs such as adriamycin or cyclophosphamide
.

The pros and cons of these regimens are still unclear, so if you want to choose chemotherapy, you still have to follow the traditional regimen, with platinum combined with adriamycin as the main treatment, but it must be emphasized that a strict definition must be established

Professor Zhang Shiqian: Screening and Diagnosis

Third, the impact of chemotherapy complications

Third, the impact of chemotherapy complications

Professor Zhang Shiqian: Chemotherapy is a double-edged sword.
It will also bring adverse reactions during treatment, which will affect the quality of life of patients, especially bone marrow suppression, gastrointestinal reactions, and hair loss
.

In the clinic, the family members of patients often only pay attention to the patient's personal experience and do not pay attention to the long-term contribution of chemotherapy, but doctors pay more attention to the overall impact of chemotherapy on human diseases

Professor Zhang Shiqian:

The side effects of chemotherapy are reversible and temporary
.

The common side effects in clinical practice can be solved by medicine, rehabilitation and other methods

【Profile of the expert】

Zhang Shiqian, Ph.
D.
, Professor, Chief Physician of Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, PhD supervisor, National Outstanding Scientific and Technological Worker, Expert of Women and Children Think Tank of Shandong Provincial People's Government , Excellent Scientific and Technological Worker of Shandong Province, National Health and Family Planning Commission? Medical Reference Report Executive editor of Obstetrics and Gynecology Channel, candidate for director of Chinese Society of Oncology and Reproductive Sciences, Chinese Medical Doctor Association, director of Minimally Invasive Gynecological Oncology Committee of Chinese Medical Doctor Association, deputy director of Reproductive Tract Disease Diagnosis and Treatment Branch of Chinese Association of Eugenics, Gynecology Department of Chinese Anti-Cancer Association Standing member of the Oncology Committee, member of the Standing Committee of the Chinese Medical Education Association Gynecology Committee and Vice Chairman of the Cervical Lesions Branch, standing member of the Chinese Research Hospital Association Gynecological Oncology Committee, standing member of the Gynecological Branch of the Chinese Geriatrics Association, Vice Chairman of the Shandong Pain Medicine Association Chairman, Chairman of the Obstetrics and Gynecology Professional Committee, Chairman of the Shandong Gynecological Oncology Rehabilitation Branch, Chairman of the Gynecological Committee of the Shandong Geriatrics Association, Vice Chairman of the Gynecological Oncology Committee of the Shandong Association of Integrated Traditional Chinese and Western Medicine, Director of the Shandong Anti-Cancer Association, Deputy Chairman of the Gynecological Oncology Branch, Deputy Editor-in-Chief of "Physician Forum? Contemporary Obstetrics and Gynecology" of Shandong Medical Association, standing editorial board member of "Gynecology and Genetics", Chinese version of "Obstet Gynecol", "Chinese Journal of Practical Gynecology and Obstetrics", etc.
Editorial board member
.

National Natural Fund 2, presided over the Shandong Province Science Foundation and ministerial research projects and other provinces four, nearly five years, published more than 60 papers

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