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As we age, our tissues accumulate sensiagest cells.
these cells, though alive, no longer grow, do not function, and lose the ability to properly regulate the "output" of the gene. In the study, published
by BMC Cell Biology, a team led by Lorna Harries, professor of molecular genetics at the University of Exeter, has found a way to make sensiagest cells "younger."
processed with this method for some time, the senescent cells begin to divide and have longer telomeres.
(Tip: Telomeres are a protective structure at the end of chromosomes that are essential to maintaining the stability of the human genome.
telomere shortening and cell division are considered signs of aging.
) In fact, the new findings are based on previous research by the University of Exeter.
earlier, studies confirmed that a class of genes called splicing factors, which are essential to ensure that genes function to the full potential, are gradually shut down as humans age.
in the new study, scientists found that this "off" of the cutting factor can be reversed by chemicals.
splicing factor "re-open" makes the sensitifying cells not only look younger physically, but also begin to act more like younger cells and begin to divide.
specifically, the chemical used by the researchers is called resveratrol analogues.
the compound is based on resveratrol, a substance that is naturally found in red wine, dark chocolate, red grapes and blueberries. people who
focus on anti-aging research must be no strangers to resveratrol, which is considered a "longevity drug potential stock" with metformin and rapamycin. Dr. Eva Latorre, the first author of the
paper, was surprised by the extent and speed at which senescent cells change. "When I saw some of the cells in the petri dish rejuvenate, I couldn't believe it, " she says,
.
these old cells look like young ones.
I've repeated the experiment many times, and every time it turns out.
I'm very excited about the significance and potential of this study.
", it is well known that as people get older, they are more likely to suffer from stroke, heart disease and cancer.
the discovery could lead to a potential cure to help people age "healthier" and not suffer from diseases that come with it.
.