Prostate: Investigation of predictors of recurrence in holmium laser enucleation of prostate

Benign prostatic hyperplasia (BPH) is one of the most common causes of lower urinary tract symptoms (LUTS) in men
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Surgical treatment is usually the treatment of choice for patients with moderate/severe drug-refractory LUTS

Holmium laser enucleation of the prostate (HoLEP) is one of the most studied surgical techniques for benign prostatic hyperplasia (BPH), and its efficacy in relieving symptoms has been widely described
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However, there is little evidence on predictors of symptom recurrence

The researchers analyzed data on patients with benign prostatic hyperplasia who received consecutive HoLEP treatment at two tertiary referral centers from 2012 to 2015
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At 12 months, 24 months, and 60 months of follow-up, the functional results were evaluated by urine flow rate parameters and the International Prostate Symptom Score (IPSS) questionnaire

A total of 567 patients’ data are available for analysis
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Before surgery, the median prostate volume of all patients was 80cc, the median PFR was 8ml/s, and the median PVR was 100cc

Multivariate logistic regression analysis of predictors of symptomatic patients 60 months after HolEP surgery

In summary, no matter which technique is selected, HoLEP can alleviate symptoms lastingly
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For patients with important symptoms or high PVR before surgery, the risk of recurrence of symptoms should be carefully considered

Matteo Droghetti Angelo Porreca, Lorenzo Bianchi et al.