-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Complex genomes are characterized by large amounts of tandemly repeated
DNA
that can comprise up to several percent of the genome in some organisms (
1
,
2
). The analysis of the organization of this type of DNA presents certain challenges owing to its repetitive nature, genomic distribution, and large array size. The availability of the large-scale resolution of pulsed-field gel electrophoresis (PFGE) (
3
,
4
) has allowed an increased understanding of the genomic organization of long arrays of tandemly repeated DNA, including their overall size and internal polymorphic variation. Such analyses are useful for long-range physical mapping of the large blocks of repetitive DNA characteristic of complex genomes and allow genetic information to be obtained for these loci. Although described here for human centromerit alpha satellite DNA, these techniques are also applicable to other repetitive and multicopy DNA families.