Qian Wenfeng's team found that genetic interoperability networks play a role in the decision-making of gene sequences on chromosomes

nucleotymes are linearly arranged on chromosomes. It has been reported in several species that the sequence of genes is not completely random. However, the evolutionary mechanism of the orderly arrangement of genes is still unclear.
Wenfeng Research Group of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences speculated that genetic interoperability networks were an important factor affecting gene sequentiality, based on evolutionary theoretical models. The researchers made evolutionary simulations of gene sequence formation and systematically analyzed yeast genetic interoperability networks, and found that genetic interoperability networks are important factors in determining the order of genes on chromosomes. Further, the researchers successfully used a network of genetic interoperability to predict the genetic order of brewing yeast. The study reveals the important role of genetic interoperability networks in gene sequence evolution, and also broadens our understanding of the laws of genomic coding.
the findings were published online October 3, 2017 in
(DOI:10.1093/molbev/msx264). Yang Yufei, a former assistant researcher at Qian Wenfeng Research Group, and Cao Wenqing, a doctoral student, are the first authors of the article. The research was funded by the National Natural Science Foundation of China. (Source: Science.com)