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    Home > Active Ingredient News > Study of Nervous System > Radiology: Application of BOLD functional magnetic resonance imaging in moyamoya disease

    Radiology: Application of BOLD functional magnetic resonance imaging in moyamoya disease

    • Last Update: 2021-07-27
    • Source: Internet
    • Author: User
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    Assessing the risk of cerebral ischemia is a basic task in the diagnosis of cerebrovascular diseases .


    Assessing the risk of cerebral ischemia is a basic task in the diagnosis of cerebrovascular diseases .


    In clinical and scientific research, the need to measure cerebral vascular injection reserve certain drugs (e.


    Recently, a study published in the Journal of Radiology determined the optimal time filtering window by comparing RS CVR mapping with the reference standard CO2 inhalation CVR, further optimized and evaluated the RS CVR MRI technology, and proved that it is compatible with neurosurgery treatment The relationship provides a more convenient and intuitive imaging method for clinical evaluation of cerebral vascular reserve, and provides new ideas for further evaluation of cerebral ischemia


    This study retrospectively evaluated in December 2008 to September 2010 period were collected in 170 healthy controls RS BOLD functional MRI data will be compared with the reference standard RS CVR mapping CO2 inhalation CVR to determine the best time to filter Optimal frequency range


    A total of 170 healthy subjects (mean age ± SD, 51 ± 20; 105 females) and 50 Moyamoya disease (mean age, 41 ± 12; 43 females) 100 large cerebral hemispheres were Evaluation


     

    Figure 1 (A) RS, CVR maps and TOF magnetic resonance angiography (MRA) images of three representative moyamoya disease patients


    Figure 1 (A) RS, CVR maps and TOF magnetic resonance angiography (MRA) images of three representative moyamoya disease patients


     

    Figure 2 Box plot shows: (A) resting state (RS), (B) cerebrovascular reactivity (CVR) value of inhaled carbon dioxide between the two cerebral hemispheres with or without revascularization


    Figure 2 Box plot shows: (A) resting state (RS), (B) cerebrovascular reactivity (CVR) value of inhaled carbon dioxide between the two cerebral hemispheres with or without revascularization


    This study shows that the use of resting state (RS) blood oxygen level dependent (BOLD) functional MRI to evaluate cerebrovascular reactivity (CVR) mapping provides a non-invasive and convenient imaging method for measuring cerebral vascular reserve.


    Original source:

    Peiying Liu , Gongkai Liu , Marco C Pinho ,et al.


    Liu Peiying , Gongkai Liu , Marco Pinho C , et Al.
    Cerebrovascular Reactivity, the Using the Mapping Resting State BOLD-Functional in Healthy Adults and the MRI of Moyamoya Disease Patients with .
    The DOI: 10.
    1148 / radiol.
    2021203568 10.
    1148 / radiol.
    2021203568

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