Radiology: T1MRI hyperintensity in stable coronary artery disease is intraplaque hemorrhage rather than lipid components

T1-weighted MRI unscanned coronary hyperintensity plaques (HIPs) are associated with poor clinical outcomes
.

In the carotid artery, intraplaque hemorrhage (IPH) is considered to be the main source of hyperintensity

Shunya Sato et al.
compared CATCH MRI scans and near infrared spectroscopy (NIRS) intravascular ultrasound (IVUS) images to determine whether the main substrate of HIPs on T1-weighted images is intraplaque hemorrhage (IPH) or lipids
.

The research results were published in the journal Radiology

Blood vessel

 

The study retrospectively included consecutive patients who underwent CATCH MRI before NIRS IVUS at two centers from December 2019 to February 2021
.

On MRI, HIP is defined as the ratio of plaque to myocardial signal intensity of at least 1.
4
.

In IVUS (reporting on behalf of IPH) the presence of an echo band was recorded

On MRI, HIP is defined as the ratio of plaque to myocardial signal intensity of at least 1.

A total of 205 plaques were analyzed in 95 patients (median age 74 years; interquartile range [IQR], 67-78 years; 75 men)
.

MRI of HIPs (n = 42) mainly IVUS echo-free regions (79% [33/42] vs 8.

NIRS in _4mm

Scatter plot of plaque-myocardial signal intensity ratio (PMR) and maximum lipid core load index (maxLCBI _{4 mm} )

_{4 mm}

In the multivariate model, HIPs were independently correlated with the anechoic zone (odds ratio, 24.
5; 95% confidence interval: 9.
3, 64.
7; P<0.
001), but not related to lipid-rich plaques (odds ratio, 2.
0; 95 % Confidence interval: 0.
7, 5.
4; P = 0.
20)
.

In stable coronary artery disease, the main substrate of T1-weighted MRI high signal plaque is intraplaque hemorrhage, not lipids
.

In stable coronary artery disease, the main substrate of T1-weighted MRI high signal plaque is intraplaque hemorrhage, not lipids
.

In stable coronary artery disease, the main substrate of T1-weighted MRI high signal plaque is intraplaque hemorrhage, not lipids

Sato S, Matsumoto H, Li D, et al.

Sato S, Matsumoto H, Li D, et al.
Coronary High-Intensity Plaques at T1-weighted MRI in Stable Coronary Artery Disease: Comparison with Near-Infrared Spectroscopy Intravascular US [published online ahead of print, 2021 Dec 14].
Radiology.
2021;211463.
doi:10.
1148/radiol.
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