Rapid Sequencing of Parasite rRNA
-
Last Update: 2021-01-30
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
The phylogeny of a large number of parasite species is still entirely based on morphological and physiological features. However, the reliability of such criteria becomes highly questionable, especially for species exhibiting a low level of organismal complexity. The advent of modern nucleic acid sequence technology now provides the opportunity for critical reexaminations of existing taxonomies and for improved measurements of phylogenetic distances (
1
). Nucleotide sequence comparisons not only furnish a rich amount of information, but their one-dimensional character also makes them much less susceptible to subjective judgements and particularly well suited to quantitative evaluation. Over recent years the accumulation of sequence data on ribosomal genes from a variety of prokaryotic and eukaryotic species has revealed the outstanding properties of rRNAs as molecular indicators of phylogenetic relationships (
1
,
2
). Their remarkable interest stems not only from their universal occurrence in all organisms, or from the high information content of their nucleotide sequence, but also from their mosaic pattern of structural variation, with an interspersion of domains showing significantly different rates of sequence divergence (
3
–
5
). Owing to the presence of a series of highly conserved domains, rRNAs can serve as general indicators, even among the most distant living species (
6
–
11
).
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
