Recent studies show that tear samples can be used to predict diabetic complications

Recently, a new study shows that the signal molecule level of substance P nerve cells in tear samples is an important marker of nerve damage caused by diabetes The research was published in American vision Researchers from the University of New South Wales in Australia measured the level of substance P in the tear samples of diabetic patients, through which the risk of diabetic neuropathy can be assessed The researchers pointed out that the level of substance P in the tear samples of diabetic patients has a direct relationship with early corneal neuropathy, and the abnormal level of substance P may lead to corneal neuropathy The development of ulcers and the difficulty of wound healing in diabetic patients Substance P is a kind of neuropeptide, which can help wound healing At the same time, substance P also participates in corneal maintenance The surface protection of substance P plays a key role in corneal fine neural network In the study, researchers tested tear samples from 9 diabetics and 17 nondiabetics, mainly measuring the content of substance P in tears In this study, scientists hope to predict the risk of diabetic neuropathy by noninvasive detection of substance P (http:// The results showed that the substance P level of diabetic group was lower than that of healthy group (http:// Through confocal microscopy, the density of corneal nerve fiber in diabetic group was significantly reduced, which indicated the loss of corneal nerve fiber The relationship between substance P and corneal nerve density suggests that substance P may be a potential biomarker of corneal nerve health The researchers say they hope to prevent this diabetes complication by measuring substance P levels.