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Today, AstraZeneca and Merck (MSD) jointly announced that the PARP inhibitor Olapali (English trade name Lynparza), jointly developed by the two parties, is used in the treatment of high-risk HER2-negative early stage with germline BRCA mutation (gBRCAm) Positive results were obtained in phase 3 clinical trials of breast cancer
The Phase 3 clinical trial called OlympiA is a double-blind, placebo-controlled multicenter clinical trial
The results of the test showed that after 3 years of treatment, 85.
▲Efficacy results of olaparib in the Phase 3 clinical trial of OlympiA (picture source: reference [1])
In 2020, approximately 2.
Note: The original text has been deleted
Reference materials:
[1] Lynparza reduced the risk of cancer recurrence by 42% in the adjuvant treatment of patients with germline BRCA-mutated high-risk early breast cancer in OlympiA Phase III trial.