Regulation of the metabolism of connective tissue

NetworkSection IV Connective
Tissues
Metabolism Regulation Growth
Hormone
promotes the synthesis of
proteins
while also promoting the synthesis of protein polysaccharies and collagen. Animal experiments have shown that growth hormone's cartilage growth effect, at least in part through growth regulator A (somatomedin A), stimulates the proliferation of cartilage cells and sulfates mixed with protein polysaccharides, so also known as "sulphate factor."thyroxine promotes the breakdown of protein polysaccharine, and mucus edema often occurs in hypothyroidism, which is associated with the weakening of protein polysaccharine decomposition in the off-skin accumulation.both testosterone and estrogen promote the synthesis of hyaluracin, while adrenal corticosteroids stabilize lysosomes and reduce the release of lysosome enzymes, thus maintaining the stability of protein polysaccharides. Insulin can promote the synthesis of glycamine polysaccharides, which may be associated with slow wound healing, susceptible to infection and complications of vasody. Glucoticoids have an effect on the synthesis and decomposition of collagen, and long-term use can produce side effects such as thinning of the skin, osteoporosis and delaying wound healing.