Research on the development of biomedical industry in Suzhou Industrial Park

By Liao Yitao In recent years, Suzhou Industrial Park has vigorously promoted the high-quality development of biomedical industry, guided talents, funds, projects and carriers to gather in the park with the development orientation of industry city integration, international development and operation mode, diversified industrial operation and other development strategies, and gradually formed a cluster of innovative talents, innovative subjects, outstanding innovation achievements, excellent innovation ecology and innovative vitality In the comprehensive evaluation of National Economic Development Zone issued by the Ministry of Commerce, the ecological environment of biomedical industry of Fafa ranked first for three consecutive years, and ranked among the ranks of building world-class high-tech parks In 2018, Suzhou Industrial Park achieved a total regional GDP of 257 billion yuan, with the output value of high-tech industry accounting for more than 70% of the industrial output value above the designated level In the comprehensive evaluation of the National Economic Development Zone released by the Ministry of Commerce, the park ranked first for three consecutive years (2016, 2017 and 2018), and ranked among the ranks of building world-class high-tech parks The biomedical, nanotechnology application and artificial intelligence industries have taken shape In 2018, the output value was 78 billion yuan, 65 billion yuan and 25 billion yuan respectively, up 27%, 30% and 38% year-on-year According to flint creation database, as of September 31, 2019, Suzhou Industrial Park has 4047 medical and health enterprises, 114 high-tech biomedical enterprises, 1 Top 100 pharmaceutical enterprises and 9 listed enterprises (new third board) Table 1 some key enterprises of biomedical industry in Suzhou Industrial Park 1 Since its establishment in 1994, Suzhou Industrial Park has gone through the stages of starting, accelerating development, leapfrog transformation and international promotion The park always follows the planning concept of "integration of industry and city", introduces advanced concepts such as "white land", "grey land" and "elastic green land", implements elastic control on the plot, forms management and service concepts in line with international standards through the construction of international cooperation platform, constructs a development mode driven by innovation, and vigorously develops biomedical, artificial intelligence, nanotechnology and other wars The new industry will realize the magnificent transformation from the traditional industrial park to the new high-tech industrial zone Figure 1 overview of the development of Suzhou Industrial Park 2 Suzhou Industrial Park has formed Dushu Lake Science and Education Innovation Zone, Jinji Lake Central Business District, Zhongxin ecological science and Technology City, comprehensive bonded zone, high-tech industrial zone, Yangcheng Lake Leisure Tourism Resort and other functional areas There are 19 "neighborhood centers", 2 business service sub centers and one central shopping mall planned in the whole district Including various urban functions such as industry, residence and commerce, the functional ratio is 39.6% for residence, 37.9% for industry, 22.5% for supporting facilities, and 40% for greening The advanced integrated development plan of industry and city has laid a good foundation for office, entrepreneurship, communication, life and living environment for enterprises and talents gathering in the park The biomedical industry of Suzhou Industrial Park is mainly distributed in the first phase (the former Suzhou Biological Nanotechnology Park) and the second phase of Suzhou biomedical industrial park located in Dushu Lake Science and Education Innovation Zone Suzhou biomedical industrial park is a professional science and technology carrier of independent innovation of biotechnology and nanotechnology, which is mainly constructed by the government of Suzhou Industrial Park to promote the science and technology leapfrogging plan of Suzhou Industrial Park It is also the main innovation base of cultivating the development of biotechnology industry in Suzhou Industrial Park Table 2 spatial layout of Suzhou biomedical industrial park At present, Suzhou Industrial Park has formed characteristic industrial clusters of new drug creation, medical devices (including in vitro diagnosis), biotechnology, etc The main application research focuses on gene synthesis and editing, reproduction and genetics, tumor liquid biopsy, drug target and drug resistance research, health population detection services and other fields At the same time, a variety of biomedical related industries emerged, including biotechnology, pharmaceutical R & D and production, medical devices, consulting services, trade and so on According to the development plan of Suzhou biomedical industry (2018-2022), Suzhou Industrial Park will focus on the development of biomedical industry segments such as macromolecular Biopharmaceutics, micromolecular chemicals, medical imaging, in vitro diagnosis, plant intervention equipment and medical materials in the next five years, and further improve the level of industrial agglomeration （1） Innovation achievements 1 Clinical trials According to the flint creation database, as of September 30, 2019, the number of clinical trials of drugs in Suzhou Industrial Park was 200, accounting for 2.2% of the national total Among them, the number of clinical trials of chemical drugs and biological products accounted for 51.5% and 43.0% respectively, and most of the products were still in clinical stage I, accounting for 70.5% (104 / 200) Figure 2 distribution of clinical trials of drugs in Suzhou Industrial Park Data source: flint creation 2 New drug application Among the new drug applications accepted by CDE, the number of class 1, class 2 and class 3 new drug applications in Suzhou Industrial Park accounts for 1.2% of the total number of new drug applications in China, and mainly class 1 new drug applications Figure 3 application of new drugs in Suzhou Industrial Park accepted by CDE in China Data source: CDE, Flint creation 3 Drug priority evaluation Among the 729 drugs listed in the list of drug priority evaluation by CDE, Suzhou Industrial Park has 8 drug priority evaluation varieties, accounting for 1.1% of the national total 4 Special approval of medical devices Up to now, among the 803 special approval lists of medical devices publicized nationwide, Suzhou Industrial Park has 11, accounting for 1.4% 5 Approval of domestic drugs The number of domestic drugs approved in Suzhou Industrial Park is 199, accounting for 0.1% of the total amount of the country, among which chemical drugs are the main one, while the number of domestic biological drugs approved is only 2 6 Invention patent Suzhou Industrial Park has applied for 4280 invention patents and granted 1491 invention patents, accounting for 0.8% of the national total 7 Consistency evaluation of generic drugs Among the 489 varieties that have passed the consistency evaluation of generic drugs, Suzhou Industrial Park has 13 varieties, accounting for 2.6% 8 Listing of class II and III medical devices Suzhou Industrial Park has 671 listed class II and class III medical devices, accounting for 1% of the national total （2） Innovation resources 1 Scientific research platform The park has one national laboratory, 13 "national team" scientific research institutes, nearly 500 new research and development institutions, more than 20 international cooperation platforms, more than 8 million square meters of various scientific and technological carriers, more than 30 public technology service platforms, more than 20 national innovation bases, including the Institute of Medicine, the Institute of biochemical cells and the Institute of systematic medicine of the Academy of Medical Sciences Institute, as well as cold spring port laboratory 2 College resources Dushu Lake Higher Education Zone in the park draws lessons from the successful experience of foreign higher education cities and towns, adopts the urban planning mode of infrastructure sharing and campus mutual opening and integration, and attracts Liverpool University of Xijiao, International College of National People's Congress, Suzhou Research Institute of National University of Singapore, Oxford University, etc to settle down, becoming the first-class higher education talent training base in China and research transfer of high-tech achievements Chemical base 3 Innovative talents The park is positioned to lead industrial innovation with high-end talents, and vigorously promote the gathering of high-end talents by introducing and cultivating advantageous enterprises, gathering top international scientific research institutions and increasing policy support According to flint database, as of September 30, 2019, Suzhou Industrial Park has gathered 90 national level talents, 41 provincial level talents and 25 municipal level talents in biomedical field With 68 national talent project candidates and 16 Chinese and foreign academicians leading the team in the field of biomedicine, the number of professional and technical talents in the field of biomedicine has exceeded 40000 （3） Innovation capital 1 Investment and financing According to the flint database, as of September 30, 2019, the total amount of disclosed financing in the field of biomedicine of Suzhou Industrial Park reached 13.351 billion yuan, with the overall investment and financing rounds concentrated in Angel round, round a and round B The participating enterprise financing institutions in the park are the world's leading and well-known biomedical funds in China, such as Fidelity Fund, Lilly Asia Fund, Softbank China, Singapore Temasek, Aobo capital, Junlian capital, yaomingkant, Qiming venture capital, etc Figure 4 distribution of disclosed financing rounds of enterprises in Suzhou Industrial Park Data source: flint creation 2 Revenue of listed companies According to the flint database, nine listed companies (new third board) in the biomedical field of Suzhou Industrial Park achieved revenue of 662 million yuan and profit of 127 million yuan in the first half of 2019 （4） Innovation policy In recent years, in order to speed up the development of biomedical industry, Suzhou Industrial Park has issued a series of policy documents, such as "measures of Suzhou Industrial Park on accelerating the construction of world-class high-tech industrial park for scientific and technological innovation support", "implementation rules of Suzhou Industrial Park on improving scientific and technological innovation capacity (2018)" "implementation measures of Suzhou Industrial Park on further promoting the development of biomedical industry", etc It involves talents, technological innovation, scientific and technological innovation support and other aspects Further enhance the competitive advantage of the pharmaceutical industry in the province and enhance the industrial influence 1 Suzhou Industrial Park implements the management mode of separating administrative enterprises The main administrative body is the park management committee, which, as the agency of Suzhou municipal government, comprehensively exercises the sovereignty and administrative functions in the administrative area The development body of the park is composed of consortiums of China and Singapore The Chinese consortiums are CSSD, which is funded by 14 large domestic enterprise groups, including COFCO, COSCO, Sinochem and Huaneng The characteristic operation and management mode has injected the fast and stable development power into the park 2 China Singapore Suzhou Industrial Park Development Co., Ltd (CSSD), jointly established by China and Singapore, is controlled by China Through the form of "functional platform subsidiary + project subsidiary", the group aims to build a green and low-carbon city with advanced planning and design, efficient global investment, perfect municipal public supporting facilities and strong urban operation system integration, and promote the comprehensive, coordinated and sustainable development of regional economy and society The functional platform company provides district supporting services for each project development The project subsidiary is responsible for the district's business from the first level development of land, to the second level construction of property, to the third level industrial city operation, covering the whole process of park development Figure 2 organizational structure of new group Photo source: Official Website of China New Suzhou Industrial Park Development Group Co., Ltd （1） Building industrial organization capacity Construction of "small government and large society" business attraction and pro business operation service system 1 Business promotion mechanism Through the reform of large departments, the "five one" grass-roots government governance structure of "one seal for examination and approval, one team for law enforcement, one department for market, one platform for credit, and one network for service" has been formed; with reference to Singapore's experience, the concept of Pro business service has been practiced, and the one-stop service center, enterprise development service center and other public service platforms have been promoted to adapt to the transformation and development We will strictly regulate the handling of economic and social affairs in accordance with the law and build an international business environment 2 Investment strategy The park uses the offices of the Economic Development Bureau of the Ministry of trade and industry of Singapore located around the world to publicize, through a wide coverage and efficient investment attraction network and platform, to search for customers with market-oriented and strategic orientation, introduce foreign investment by various sales methods, at the same time, build the image and popularity of the park, and expand multilateral channels to discover and win investment attraction goals （2） Build the ability of Talent Gathering Relying on high-level talent introduction platform, attracting domestic and foreign professionals to settle in the park with excellent policies and personalized talent services 1 Ways of Talent Gathering Contact and cooperation with organizations of overseas students and overseas institutions,