The Gao Fu team of the Institute of Microbiology, Chinese Academy of Sciences recently reported on the "atypical" interaction mechanism between the costimulatory receptor glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR) and its ligand GITRL.
TNF "superfamily" related molecules are the key to natural/acquired immune regulation and function.
Assistant researcher Zhao Min of the Institute of Microbiology and Fu Lijun, a postgraduate jointly trained by Jiangxi Science and Technology Normal University, are the co-first authors of the study.
Related paper information: https://doi.
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