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Chlorine disinfectant is a kind of disinfectant widely used in daily life.
The development and spread of microbial antibiotic resistance has posed a serious threat to global public health.
The study shows that disinfectants act on free ARGs and recipient bacteria at the same time, which intensifies the transformation performance of ARGs, because disinfectants can cause the recipient non-antibiotic resistant bacteria to trigger oxidative stress, stress and DNA repair reactions, opening up Membrane channels, thereby enhancing the natural transformation performance of the recipient bacteria, and ultimately leading to the uptake of free ARGs by the recipient bacteria.