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Researchers develop intravenous therapy for sepsis

 Last Update: 2022-05-15
 Source: Internet
 Author: User

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Researchers at Purdue's School of Pharmacy and Engineering are developing a patent-pending treatment that could impact the lives of millions of Americans each year

The Centers for Disease Control and Prevention reports that at least 1.

A Purdue University team led by Yoon Yeo has developed biocompatible nanoparticles to treat sepsis through an intravenous system

Polymyxin B, a traditional antibiotic that inactivates endotoxins that cause certain types of sepsis, may be too toxic for systemic application, Yeo said

"Our nanoparticle formulation reduced the dose-limiting toxicity of polymyxin B without losing its ability to inactivate endotoxin," Yeo said

In a mouse model of sepsis, 100 percent of mice treated with Purdue nanoparticles were spared from excessive inflammation and survived

"This technology promises to be a safe, convenient option for patients and physicians

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