Researchers establish a new prediction algorithm for prophage de novo

The team of Wang Xiaoxue, a researcher at the South China Sea Institute of Oceanology, Chinese Academy of Sciences, has established a new algorithm for prediction of prophage de novo that does not rely on the similarity of phage gene sequence .

After the virulent phage infects the bacterial host, it multiplies in large numbers and lyses the host cell to release the progeny phage particles

Gentle bacteriophages can form a long-term symbiotic relationship with the host, and their integration and excision can destroy or restore the normal function of the host's genes, which is an important way to regulate host gene expression

In order to solve the above problems, Tang Kaihao et al.

This research work has been co-funded by the National Science Foundation for Outstanding Youth, the key projects of the National Science Foundation of China's Hydrosphere Microbiology Major Research Program, the General Program, and the National Key Research and Development Program

Related paper links: https://academic.

Prophage Tracer download address: https://github.

Figure 1 Prophage Tracer process