Researchers used nanosiliconate clay to improve 3D bioprinting of hydrogels.

Hydrogels are very useful in 3D bioprinting due to their compatibility with the human body.
now, researchers are studying 3D-printed hydrogels and expanding the use of this material.
Recently, researchers from the Technical University of Dresden in Germany and the University of Southampton in the United Kingdom published a paper in the journal BioFabrication entitled "Developing a clay-based bioink for 3D cell printing for bone applications", which details the potential for the use of multifunction materials in tissue engineering.
researchers hope to one day print out the entire transplanted organ.
" 3D-printed hydrogel containing cells has developed into a very promising way to build customized or complex organizational structures.
, however, it is still difficult to print structures that have both high shape fidelity and cellular vitality, " the researchers said.
to meet this printing challenge, the team began using Laponite, an artificial nanosiliconate clay.
by combining alginate and methyl cellulose that make 3D printing easier, the researchers created a bioink.
use this material, they can print out the new bracket in 3D.
"After extrusion, about 70%-75% of human stem cells survive, and cell vitality remains in the print structure for more than 21 days," the paper reads.
researchers note that Laponite offers many benefits, including "drug delivery performance."
they used bovine serum albumin and vascular endoderma growth factors in biological ink.
We have shown that Laponite's addition significantly lasts longer than the alginate-methyl cellulose mixture that did not add Laponite," the researchers said.
, they found that using Laponite resulted in better manufacturing techniques, improved "shape fidelity" and the release of active agents.
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