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| "Science": SARS-like viruses may infect humans from animals hundreds of thousands of times each year |
In the past 20 years, two new coronaviruses broke out globally: SARS-CoV and SARS-CoV-2
.
The former caused an outbreak of severe acute respiratory syndrome (SARS) in 2003; the latter caused an outbreak of COVID-19
This conclusion comes from a paper on the medical preprint website medRxiv
.
The paper believes that the SARS epidemic and the COVID-19 epidemic are just more significant examples of bat-related coronaviruses infecting humans, and more have not been discovered
The aforementioned paper is entitled "A strategy to assess spillover risk of bat SARS-related coronaviruses in Southeast Asia"
.
Corresponding authors include Peter Daszak , an internationally renowned virologist and chairman of the EcoHealth Alliance, a non-profit organization
Chairman
Virologist Angela Rasmussen told Science that the number is shocking, because humans still have little knowledge of zoonotic diseases
.
In zoonotic diseases, bats play an unusual role
In an interview with The Paper ( a well-known virologist in China said that for ordinary people, they noticed that bats are carrying powerful viruses, such as SARS and Ebola that broke out in the 21st century.
, Middle East Respiratory Syndrome, etc.
are all related to bats
.
Peter Daszak did a very careful study and compared the amount of virus carried by each heterologous animal.
"Strategies for Assessing the Spillover Risk of SARS-related Coronavirus in Bats in Southeast Asia" maps the habitats of 23 bat species known to carry SARS-related coronaviruses, and then superimposes them with data on human settlements to create a map of potential infection hotspots
.
They found that nearly 500 million people live in areas where relevant coronavirus spillovers may occur, including northern India, Nepal, Myanmar and most parts of Southeast Asia
map
"This is a detailed analysis of where the next SARS or COVID-19 virus is most likely to appear on the earth," Daszak said.
These maps can be improved by changing human behavior in high-risk areas and targeted monitoring.
Early detection of new coronavirus outbreaks to guide how to reduce spillover effects
.
Daszak also believes that SARS-CoV-2 comes from the wild
map
The paper also disclosed that a small survey conducted before the COVID-19 outbreak showed that some residents of Southeast Asia had antibodies against SARS-related coronavirus in the serum
.
Combining these data with data on how often people encounter bats and how long the antibodies remain in the blood, the researchers calculated that there are about 400,000 undetected human cases of coronavirus in the area each year
However, most of these coronavirus infections may not yet have the ability to spread from person to person
.
"Many of these coronaviruses may not be able to spread from one person to another, but these viruses can cause people to get sick.
It's just that these coronaviruses have been misdiagnosed locally or have never been diagnosed," Daszak cited as an example.
" For example, a farmer in Myanmar is unlikely to go to the clinic, he just seems to have a cough
.
"
Vincent Munster, a virologist at the National Institute of Allergy and Infectious Diseases, who studies coronaviruses, said that this work is a preliminary exploration of the risk factors for the spread of viruses from animals to humans
.
He said that this has at least sent a clear signal: the extracorporeal effects of zoonotic pathogens from wild animals are more frequent than previously recognized by humans
.
