Scientific research found that the diversity of new coronaviruses in intestinal samples is higher than that of the respiratory tract

China News Service, Guangzhou, February 23 (Cai Minjie) The State Key Laboratory of Respiratory Diseases of Guangzhou Medical University announced on the 23rd that the team of Professor Zhao Jincun from the laboratory has cooperated with Shenzhen Huada Life Sciences Research Institute and other units to discover individual patients with new coronary pneumonia The variation and evolution characteristics of virus quasispecies at different time points and different physiological parts (respiratory tract, digestive tract) provide important theoretical guidance for the evolution of the new coronavirus and the emergence of mutant strains.

Related papers were published online in the professional journal "Genome Medicine" on February 23, 2021.

The new coronavirus is highly pathogenic and spreads quickly from person to person.

The above study collected samples of patients with new coronary pneumonia at consecutive time points and multiple types, including: nasopharyngeal swabs, sputum, stool, urine, gastric mucosa, etc.

The study found that the proportion of virus-related sequences in clinical samples deep-sequencing has a certain correlation with the fluorescence quantitative CT value.

In addition, the research team's comparative analysis found that the diversity of new coronaviruses in intestinal samples is higher than that in respiratory samples.

The relevant person in charge of the research team said that "whether intestinal samples are more likely to produce mutant strains" is an important research direction in the future, and eventually more research is needed to clarify whether or not.

According to reports, the main research areas of the State Key Laboratory of Respiratory Diseases of Guangzhou Medical University are aimed at clinical and basic research on respiratory diseases: sudden major respiratory infectious diseases and lung injury, bronchial asthma and chronic cough, chronic obstructive pulmonary disease, lung cancer Wait.