Separation of Oligosaccharides by Capillary Electrophoresis Using Buffer Modifiers
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Last Update: 2020-12-26
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Source: Internet
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Author: User
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Zone electrophoresis is the basic mode of capillary electrophoresis, and it allows separation of ions having different charge-to-sizeratios. Carbohydrates having ionic groups can also be the objects of separation by this mode. A typical example is the separationof carboxylated/sulfated oligosaccharides from glycosaminoglycans, as described in Chapter 15. Most carbohydrates, however, have no electric charge under normal conditions. Therefore, introduction of ionic tags playsan important role in zone electrophoresis of such carbohydrates.
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