Shandong University and Tsinghua University Science recently published a new paper: a new mechanism for the regulation of early human embryonic translation

On September 8, the team of Academician Chen Zijiang and Professor Zhao Han of the Reproductive Medicine Research Center of Shandong University, together with the team of Professor Jie Wei of Tsinghua University, discovered a new mechanism for the regulation of early human embryonic translation, and published a role of TPRXs in human zygotic genome in Science in the form of a long article entitled "Translatome and transcriptome co-profiling reveals.

The study mapped the translation map of the transition of human eggs to early embryos, found a set of important key transcription factors that regulate human zygote genome activation and early embryonic development, and for the first time reported species differences in the dynamic changes in translation levels between humans and mice during the transition from eggs to early embryos

The reproductive medicine research center team of Shandong University is committed to clinical and basic research on reproductive development and offspring health, and a number of original achievements have been published in top international academic journals

Article link: