Side effects of sorafenib

Sorafenib is an oral drug for the treatment of some types of advanced liver and kidney cancer It plays a role by inhibiting the protein activity that controls the replication of cancer cells Doctors often use sorafenib in combination with other cancer treatments such as radiotherapy and chemotherapy The drug can't cure liver or kidney cancer, but it can help relieve the disease and improve symptoms Protein kinases are found in all human cells They help control many physiological processes, including cell replication and death In cancer cells, however, the enzyme becomes hyperactive, leading to extensive cell regeneration rather than normal death Sorafenib can be used as a kinase inhibitor to prevent uncontrolled enzymes When the kinase is inhibited, the cancer cells are difficult to spread effectively, and the tumor will start to shrink gradually Although sorafenib can effectively regulate advanced renal cancer and liver cancer cells, there are also some side effects Because its inhibition also affects healthy cells, causing headaches, nausea, vomiting, diarrhea and stomach cramps In addition, the drug can cause fatigue, joint pain, and numbness Some patients will also have severe chest pain, rash, shortness of breath and other allergic reactions Taking sorafenib can lead to increased blood pressure, internal bleeding and heart disease It can also interact with other drugs, leading to potentially fatal complications Doctors usually carefully understand the patient's medical history and medication before recommending sorafenib to avoid serious side effects Sorafenib should be given in the dose recommended by your doctor Most adult patients need to take 400 mg tablets twice a day before meals But sometimes the dosage will be increased according to the actual situation of the patient It's important to check regularly and report any side effects in time Doctors can adjust the dosage as needed Renal cancer and liver cancer are difficult to control But a combination of kinase inhibitors such as surgery, chemotherapy, radiation and sorafenib can often make patients feel better Although a complete cure for this type of cancer is unlikely, appropriate treatment can prolong the life span and improve the quality of life of patients.